Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Lung. 2014 Apr;192(2):225-33. doi: 10.1007/s00408-013-9553-6. Epub 2014 Jan 16.
Cocaine is the most commonly used illicit drug among patients presenting at hospital emergency departments and the most frequent cause of drug-related deaths reported by medical examiners. Various respiratory problems temporally associated with cocaine use have been reported. Acute and chronic uses also are responsible for lung complications, such as pulmonary edema, alveolar hemorrhage, pulmonary hypertension, organizing pneumonia, emphysema, barotrauma, infection, cancer, eosinophilic disease, and aspiration pneumonia. Although most imaging findings are nonspecific, they may raise suspicion of a cocaine-related etiology when considered together with patients' profiles and medical histories. This literature review describes cocaine-induced diseases with pulmonary involvement, with an emphasis on high-resolution chest computed tomographic findings and patterns.
可卡因是在医院急诊部门就诊的患者中最常使用的非法药物,也是法医报告的与药物相关的死亡的最常见原因。据报道,可卡因使用与各种暂时的呼吸问题有关。急性和慢性使用也可导致肺部并发症,如肺水肿、肺泡出血、肺动脉高压、机化性肺炎、肺气肿、气压伤、感染、癌症、嗜酸性疾病和吸入性肺炎。虽然大多数影像学表现是非特异性的,但当与患者的特征和病史一起考虑时,它们可能会引起对与可卡因相关的病因的怀疑。本文综述描述了与肺受累相关的可卡因引起的疾病,重点介绍了高分辨率胸部计算机断层扫描的发现和模式。