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多参数磁共振成像在前列腺癌的管理和诊断中的应用:当前的应用和策略。

Multiparametric magnetic resonance imaging in the management and diagnosis of prostate cancer: current applications and strategies.

机构信息

Department of Urology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, NY, USA.

出版信息

Curr Urol Rep. 2014 Mar;15(3):390. doi: 10.1007/s11934-013-0390-1.

Abstract

Magnetic resonance imaging (MRI) has become increasingly used worldwide in the diagnosis and management of prostate cancer. With advances in multiparametric MRI (mpMRI) technology, such as the use of dynamic contrast-enhanced and diffusion-weighted imaging sequences, observational studies have evaluated the utility for mpMRI in the continuum of prostate cancer management, from improving the detection of clinically significant prostate cancer, to planning radical prostatectomy and radiation therapy and the early detection of local recurrence. Furthermore, the potential for advanced imaging to reduce the burden of routine serial prostate needle biopsies for men on active surveillance is a promising area of research. MRI technology continues to evolve, and the potential applications in the management of prostate cancer care will require well-designed multi-institutional prospective clinical trials and rigorous efforts to standardize reporting and improve dissemination of expertise across institutions.

摘要

磁共振成像(MRI)在全球范围内已越来越多地用于前列腺癌的诊断和治疗。随着多参数 MRI(mpMRI)技术的进步,如使用动态对比增强和弥散加权成像序列,观察性研究已经评估了 mpMRI 在前列腺癌管理连续体中的效用,从提高对临床显著前列腺癌的检测,到规划根治性前列腺切除术和放射治疗以及局部复发的早期检测。此外,高级成像有可能减少对接受主动监测的男性进行常规连续前列腺针活检的负担,这是一个很有前途的研究领域。MRI 技术不断发展,在前列腺癌治疗管理中的潜在应用将需要精心设计的多机构前瞻性临床试验,并努力规范报告和提高机构间专业知识的传播。

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