Hu Rong-Bin, Zhang Heng, Zhang Xiao-Yu, Yang Shang-Dong
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.
Chem Commun (Camb). 2014 Feb 28;50(17):2193-5. doi: 10.1039/c3cc49050e. Epub 2014 Jan 16.
Palladium-catalyzed arylation of (diisopropylphosphoryl)biphenyl skeleton derivatives by the P(O)R2 directed C-H functionalization was reported. The related products were obtained in high regioselectivity and good functional group tolerance was observed. This reaction provided a new and efficient pathway for the synthesis of polyaromatic monophosphorus ligands.
据报道,通过P(O)R2导向的C-H官能化反应,实现了钯催化的(二异丙基磷酰基)联苯骨架衍生物的芳基化反应。相关产物以高区域选择性得到,并且观察到良好的官能团耐受性。该反应为多芳基单磷配体的合成提供了一条新的有效途径。