钯催化的R2(O)P导向的C(sp2)-H乙酰氧基化反应。
Palladium-catalyzed R2(O)P directed C(sp2)-H acetoxylation.
作者信息
Zhang Heng, Hu Rong-Bin, Zhang Xiao-Yu, Li Shi-Xia, Yang Shang-Dong
机构信息
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.
出版信息
Chem Commun (Camb). 2014 May 11;50(36):4686-9. doi: 10.1039/c4cc01238k.
PMID:24658145
Abstract
A novel and efficient Pd-catalyzed C-H acetoxylation is described. The approach uses R2(O)P as a directing group to synthesize various substituted 2'-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields.
摘要
描述了一种新颖且高效的钯催化C-H乙酰氧基化反应。该方法使用R2(O)P作为导向基团来合成各种取代的2'-磷酸联苯-2-OAc化合物。值得注意的是，该反应在温和条件下操作顺畅，并且对官能团具有良好的耐受性。产物具有高选择性和高收率。
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