泊沙康唑治疗胃肠道蛙粪霉病。
Gastrointestinal basidiobolomycosis treated with posaconazole.
作者信息
Rose Stacey R, Lindsley Mark D, Hurst Steven F, Paddock Christopher D, Damodaran Thara, Bennett John
机构信息
Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Drive, Bethesda 20892, USA.
Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta 30033, USA.
出版信息
Med Mycol Case Rep. 2012 Nov 15;2:11-4. doi: 10.1016/j.mmcr.2012.11.001.
Abstract
A 67 year-old Caucasian male from Arizona presented with indolent symptoms of intestinal obstruction and hydronephrosis, found at surgery to be caused by a mass involving the terminal ileum and cecum, extending into the posterior abdominal wall and obstructing the right ureter. Histopathology was diagnostic of basidiobolomycosis. PCR of tissue and sequencing identified the fungus as, Basidiobolus ranarum. During one year of posaconazole treatment, the residual mass shrank, hydronephrosis was relieved and peripheral eosinophilia resolved.
摘要
一名来自亚利桑那州的67岁白种男性，因肠梗阻和肾积水的隐匿症状就诊，手术发现是由一个累及回肠末端和盲肠的肿块引起的，该肿块延伸至后腹壁并阻塞右输尿管。组织病理学诊断为蛙粪霉病。组织的聚合酶链反应（PCR）和测序鉴定该真菌为蛙粪霉。在接受泊沙康唑治疗的一年中，残留肿块缩小，肾积水缓解，外周嗜酸性粒细胞增多症消退。
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