Vs Vikram, Hallur Vinay, Samal Swagatika, Chouhan Mohd Imran, Bhat Sunil Jee, Kumar Pankaj, Mishra Tushar S
Department of Surgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
ACG Case Rep J. 2021 May 14;8(5):e00573. doi: 10.14309/crj.0000000000000573. eCollection 2021 May.
Gastrointestinal basidiobolomycosis (GIB) is a rare fungal infection with limited geographic distribution. However, the incidence of GIB has shown an increasing trend because of globalization and frequent traveling. GIB is commonly seen to mimic gastrointestinal malignancy and other diseases such as intestinal tuberculosis and inflammatory bowel disease. Tissue diagnosis is considered to be the gold standard for differentiating these mycotic lesions from tuberculosis and malignancy with confirmation of species performed by culture or polymerase chain reaction. The diagnosis of GIB should be conjectured in patients with suspicion of malignancy, with an inconclusive biopsy. It seems prudent to proceed with radical excision of mass early because both colonic malignancy and GIB have high mortality if untreated.
胃肠道蛙粪霉病(GIB)是一种罕见的真菌感染,地理分布有限。然而,由于全球化和频繁旅行,GIB的发病率呈上升趋势。GIB通常表现为类似胃肠道恶性肿瘤以及其他疾病,如肠结核和炎症性肠病。组织诊断被认为是将这些真菌性病变与结核和恶性肿瘤区分开来的金标准,可通过培养或聚合酶链反应来确认菌种。对于疑似恶性肿瘤且活检结果不确定的患者,应推测是否为GIB。早期对肿块进行根治性切除似乎是谨慎的做法,因为如果不治疗,结肠恶性肿瘤和GIB的死亡率都很高。