Laboratory of Biological Structure Mechanics, Chemistry, Materials and Chemical Engineering Department "Giulio Natta", Politecnico di Milano Milano, Italy.
Cardiac Unit, Great Ormond Street Hospital for Children London, UK.
Front Pediatr. 2013 Feb 26;1:4. doi: 10.3389/fped.2013.00004.
Mathematical modeling is a powerful tool to investigate hemodynamics of the circulatory system. With improving imaging techniques and detailed clinical investigations, it is now possible to construct patient-specific models of reconstructive surgeries for the treatment of congenital heart diseases. These models can help clinicians to better understand the hemodynamic behavior of different surgical options for a treated patient. This review outlines recent advances in mathematical modeling in congenital heart diseases, the discoveries and limitations these models present, and future directions that are on the horizon.
数学建模是研究循环系统血液动力学的有力工具。随着成像技术的不断改进和详细的临床研究,现在可以构建用于治疗先天性心脏病的重建手术的患者特异性模型。这些模型可以帮助临床医生更好地理解治疗患者的不同手术方案的血液动力学行为。本文综述了先天性心脏病数学建模的最新进展、这些模型所呈现的发现和局限性,以及即将出现的未来方向。