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多边形曲面处理和网格生成工具,用于心脏功能的数值模拟。

Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function.

机构信息

MOX, Department of Mathematics, Politecnico di Milano, Milan, Italy.

Institute of Mathematics, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

出版信息

Int J Numer Method Biomed Eng. 2021 Apr;37(4):e3435. doi: 10.1002/cnm.3435. Epub 2021 Jan 28.

Abstract

In order to simulate the cardiac function for a patient-specific geometry, the generation of the computational mesh is crucially important. In practice, the input is typically a set of unprocessed polygonal surfaces coming either from a template geometry or from medical images. These surfaces need ad-hoc processing to be suitable for a volumetric mesh generation. In this work we propose a set of new algorithms and tools aiming to facilitate the mesh generation process. In particular, we focus on different aspects of a cardiac mesh generation pipeline: (1) specific polygonal surface processing for cardiac geometries, like connection of different heart chambers or segmentation outputs; (2) generation of accurate boundary tags; (3) definition of mesh-size functions dependent on relevant geometric quantities; (4) processing and connecting together several volumetric meshes. The new algorithms-implemented in the open-source software vmtk-can be combined with each other allowing the creation of personalized pipelines, that can be optimized for each cardiac geometry or for each aspect of the cardiac function to be modeled. Thanks to these features, the proposed tools can significantly speed-up the mesh generation process for a large range of cardiac applications, from single-chamber single-physics simulations to multi-chambers multi-physics simulations. We detail all the proposed algorithms motivating them in the cardiac context and we highlight their flexibility by showing different examples of cardiac mesh generation pipelines.

摘要

为了模拟特定于患者的几何形状的心脏功能,计算网格的生成至关重要。在实践中,输入通常是一组未经处理的多边形曲面,这些曲面来自模板几何形状或医学图像。这些曲面需要特定的处理才能适用于体积网格生成。在这项工作中,我们提出了一组新的算法和工具,旨在简化网格生成过程。特别是,我们关注心脏网格生成管道的不同方面:(1)心脏几何形状的特定多边形曲面处理,例如不同心腔的连接或分割输出;(2)生成准确的边界标签;(3)定义依赖于相关几何量的网格大小函数;(4)处理和连接多个体积网格。新算法——实现了开源软件 vmtk——可以相互组合,允许创建个性化的管道,这些管道可以针对每个心脏几何形状或要建模的心脏功能的每个方面进行优化。由于这些特性,所提出的工具可以显著加快各种心脏应用的网格生成过程,从单腔单物理模拟到多腔多物理模拟。我们详细介绍了所有提出的算法,并在心脏环境中对其进行了论证,通过展示不同的心脏网格生成管道示例,突出了它们的灵活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2cd/8244076/c25e084e87e7/CNM-37-e3435-g002.jpg

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