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结肠克罗恩病

Colonic crohn disease.

作者信息

Hedrick Traci L, Friel Charles M

机构信息

Department of Surgery, University of Virginia Health System, Charlottesville, Virginia.

出版信息

Clin Colon Rectal Surg. 2013 Jun;26(2):84-9. doi: 10.1055/s-0033-1348046.

DOI:10.1055/s-0033-1348046
PMID:24436655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3709925/
Abstract

Colonic Crohn disease is a complicated disease entity that requires a multidisciplinary effort on the part of the surgeon, gastroenterologist, and pathologist. Crohn disease affects ∼500,000 people in North America with nearly 300,000 people suffering from colonic manifestations. This represents a significant portion of the patient population in the typical colorectal surgeon's practice. As such, an intimate understanding of the disease process, presentation, and treatment options is imperative. In this article, the authors review the clinical manifestations, diagnosis, and medical and surgical treatment options with a focus on current strategies for surgical management.

摘要

结肠克罗恩病是一种复杂的疾病实体,需要外科医生、胃肠病学家和病理学家进行多学科协作。在北美,约有50万人患有克罗恩病,其中近30万人有结肠症状。这在典型的结直肠外科医生的诊疗患者群体中占了很大一部分。因此,深入了解该疾病的发病过程、临床表现及治疗选择至关重要。在本文中,作者回顾了其临床表现、诊断以及药物和手术治疗选择,重点介绍了当前的手术管理策略。

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Colonic crohn disease.结肠克罗恩病
Clin Colon Rectal Surg. 2013 Jun;26(2):84-9. doi: 10.1055/s-0033-1348046.
2
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Aspects of survival from colorectal cancer in Denmark.丹麦结直肠癌的生存情况
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Influence of caseload and surgical speciality on outcome following surgery for colorectal cancer: a review of evidence. Part 2: long-term outcome.病例数量和手术专科对结直肠癌手术后结局的影响:证据综述。第2部分:长期结局
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The influence of the surgeon's and the hospital's caseload on survival and local recurrence after colorectal cancer surgery.外科医生和医院的病例数量对结直肠癌手术后生存率和局部复发的影响。
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Crohn's disease: a surgeon's perspective.克罗恩病:外科医生的视角。
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引用本文的文献

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Use of Modified YOLOv5 Algorithm in the Differential Diagnosis of Colonic Crohn's Disease and Ulcerative Colitis on CTE Images.改良YOLOv5算法在CTE图像上对结肠克罗恩病和溃疡性结肠炎的鉴别诊断中的应用
Gastroenterol Res Pract. 2025 Jul 23;2025:1506567. doi: 10.1155/grp/1506567. eCollection 2025.
2
Pro-motility Preparation Protocol May Reduce the Rates of Failed Patency Capsule Among Patients with Crohn's Disease in Clinical Remission.促动力准备方案可能降低处于临床缓解期的克罗恩病患者胶囊通畅失败率。
Dig Dis Sci. 2024 Nov;69(11):4178-4186. doi: 10.1007/s10620-024-08670-9. Epub 2024 Oct 9.
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Differential Gene Expression of Checkpoint Markers and Cancer Markers in Mouse Models of Spontaneous Chronic Colitis.自发慢性结肠炎小鼠模型中检查点标志物和癌症标志物的差异基因表达
Cancers (Basel). 2023 Sep 29;15(19):4793. doi: 10.3390/cancers15194793.
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Machine Learning in Antibody Diagnostics for Inflammatory Bowel Disease Subtype Classification.用于炎症性肠病亚型分类的抗体诊断中的机器学习
Diagnostics (Basel). 2023 Jul 26;13(15):2491. doi: 10.3390/diagnostics13152491.
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Crohn's disease at radiological imaging: focus on techniques and intestinal tract.克罗恩病的放射影像学表现:聚焦于技术与肠道
Intest Res. 2021 Oct;19(4):365-378. doi: 10.5217/ir.2020.00097. Epub 2020 Nov 25.
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Clostridium difficile colitis: CT findings and differential diagnosis.艰难梭菌相关性结肠炎:CT 表现与鉴别诊断。
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Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases.质谱细胞术揭示了区分炎症性肠病的系统性和局部免疫特征。
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A specific gene-microbe interaction drives the development of Crohn's disease-like colitis in mice.特定的基因-微生物相互作用导致小鼠出现类似克罗恩病的结肠炎。
Sci Immunol. 2019 Apr 19;4(34). doi: 10.1126/sciimmunol.aaw4341.
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Disease-Specific Enteric Microbiome Dysbiosis in Inflammatory Bowel Disease.炎症性肠病中特定疾病的肠道微生物群失调
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本文引用的文献

1
Crohn's disease recurrence after total proctocolectomy with definitive ileostomy.全直肠结肠切除加确定性回肠造口术后克罗恩病复发。
Dig Liver Dis. 2011 Sep;43(9):698-702. doi: 10.1016/j.dld.2011.02.017. Epub 2011 Apr 6.
2
Antibiotic therapy in inflammatory bowel disease: a systematic review and meta-analysis.炎症性肠病的抗生素治疗:系统评价和荟萃分析。
Am J Gastroenterol. 2011 Apr;106(4):661-73. doi: 10.1038/ajg.2011.72. Epub 2011 Mar 15.
3
Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002).结直肠癌筛查和监测指南(中高危人群)(2002 年更新)。
Gut. 2010 May;59(5):666-89. doi: 10.1136/gut.2009.179804.
4
Colonic Crohn's disease.结肠克罗恩病
Clin Colon Rectal Surg. 2007 Nov;20(4):309-13. doi: 10.1055/s-2007-991030.
5
Long-term outcomes with ileal pouch-anal anastomosis and Crohn's disease: pouch retention and implications of delayed diagnosis.回肠袋肛管吻合术与克罗恩病的长期预后:袋保留及延迟诊断的影响
Ann Surg. 2008 Oct;248(4):608-16. doi: 10.1097/SLA.0b013e318187ed64.
6
Surgical treatment of inflammatory bowel diseases and pregnancy.炎症性肠病与妊娠的外科治疗
Best Pract Res Clin Gastroenterol. 2007;21(5):819-34. doi: 10.1016/j.bpg.2007.05.009.
7
Crohn's colitis: the incidence of dysplasia and adenocarcinoma in surgical patients.克罗恩病性结肠炎:外科手术患者发育异常和腺癌的发病率
Dis Colon Rectum. 2006 Jul;49(7):950-7. doi: 10.1007/s10350-006-0555-9.
8
Long-term outcome of surgically treated Crohn's colitis: a prospective study.手术治疗克罗恩病性结肠炎的长期结局:一项前瞻性研究。
Dis Colon Rectum. 2005 May;48(5):963-9. doi: 10.1007/s10350-004-0906-3.
9
Urgent subtotal colectomy for severe inflammatory bowel disease.针对严重炎症性肠病的急诊次全结肠切除术
Dis Colon Rectum. 2005 Jan;48(1):70-3. doi: 10.1007/s10350-004-0750-5.
10
Ten year follow up of ulcerative colitis patients with and without low grade dysplasia.对伴有和不伴有低度发育异常的溃疡性结肠炎患者进行的十年随访
Gut. 2003 Aug;52(8):1127-32. doi: 10.1136/gut.52.8.1127.