Khodarev V N, Zhemchuzhnova N L, Olempieva E V, Kuz'menko N V
Vopr Kurortol Fizioter Lech Fiz Kult. 2013 Sep-Oct(5):10-3.
This comprehensive clinical and laboratory study was designed to elucidate the antioxidant status of the volunteers before and after a course of general infrared irradiation. It was shown that the effect of high temperatures promotes the development of oxidative stress that is followed by the formation of adaptive reactions in the form of activation of antioxidant protection, enhancement of non-specific responses of the cells, increase of stability and restoration of structural homeostasis of erythrocyte membranes. The molecular mechanism of endothelium-independent vasodilation develops by the end of the treatment period; it may serve as the compensatory-adaptive reaction needed to maintain the adequate tone of the vascular wall and thereby to support the functioning of mechanisms supporting physical thermoregulation. The results of the study give evidence of the stimulatory influence of the described method on the adaptive and protective potential of the organism. It is concluded that the proposed scheme of physiotherapeutic treatment may be used for prophylactic purposes.
这项全面的临床和实验室研究旨在阐明志愿者在接受一个疗程的全身红外照射前后的抗氧化状态。结果表明，高温效应会促进氧化应激的发展，随后会形成适应性反应，表现为抗氧化保护的激活、细胞非特异性反应的增强、红细胞膜稳定性的提高和结构稳态的恢复。在治疗期结束时，内皮细胞非依赖性血管舒张的分子机制得以发展；它可作为维持血管壁适当张力从而支持物理体温调节机制功能所需的代偿性适应反应。该研究结果证明了所述方法对机体适应性和保护潜力的刺激作用。得出的结论是，所提出的物理治疗方案可用于预防目的。
