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后腹腔镜肾上腺切除术:来自最初50例病例的结果与经验教训

Posterior retroperitoneoscopic adrenalectomy: outcomes and lessons learned from initial 50 cases.

作者信息

Cabalag Miguel S, Mann G Bruce, Gorelik Alexandra, Miller Julie A

机构信息

Endocrine Surgery Unit, Royal Melbourne Hospital, Victoria, Australia.

Epworth Freemasons Hospital, Victoria, Australia.

出版信息

ANZ J Surg. 2015 Jun;85(6):478-82. doi: 10.1111/ans.12508. Epub 2014 Jan 20.

Abstract

BACKGROUND

Posterior retroperitoneoscopic adrenalectomy (PRA) is an alternative approach to minimally invasive adrenalectomy, potentially offering less pain and faster recovery compared with laparoscopic transperitoneal adrenalectomy (LA). The authors have recently changed from LA to PRA in suitable patients and audited their first 50 cases.

METHODS

Data were prospectively collected for 50 consecutive PRAs performed by the same surgeon. Patient demographics, tumour characteristics, analgesia use, operative and preparation time, length of stay, and complications were recorded.

RESULTS

Fifty adrenalectomies were performed in 49 patients. The median (range) age was 58.5 years (30-83) and the majority of patients were female (n = 33, 66.0%). The median (interquartile range (IQR)) preparation time was 35.5 (28.5-50.0) and median operation time was 70.5 (54-85) min, which decreased during the study period. After a learning curve of 15 cases, median operative time reached 61 min. PRA patients required minimal post-operative analgesia, with a median (IQR) of 0 (0-5) mg of intravenous morphine equivalent used. The median (IQR) length of stay was 1 (1-1) day, with 8 (16.0%) same-day discharges. There were four complications: one blood pressure lability from a phaeochromocytoma, one reintubation, one self-limited bleed and one temporary subcostal neuropraxia. There were no conversions to open surgery or deaths.

CONCLUSION

Our results support previously published findings that PRA is a safe procedure, with a relatively short learning curve, resulting in minimal post-operative analgesia use and short length of hospital stay.

摘要

背景

后腹腔镜肾上腺切除术(PRA)是微创肾上腺切除术的一种替代方法,与腹腔镜经腹肾上腺切除术(LA)相比,可能疼痛更轻、恢复更快。作者最近在合适的患者中从LA改为PRA,并对最初的50例病例进行了审核。

方法

前瞻性收集了由同一位外科医生连续进行的50例PRA的数据。记录患者的人口统计学特征、肿瘤特征、镇痛药物使用情况、手术及准备时间、住院时间和并发症。

结果

49例患者共进行了50例肾上腺切除术。中位(范围)年龄为58.5岁(30 - 83岁),大多数患者为女性(n = 33,66.0%)。中位(四分位间距(IQR))准备时间为35.5(28.5 - 50.0)分钟,中位手术时间为70.5(54 - 85)分钟,在研究期间有所缩短。经过15例的学习曲线后,中位手术时间达到61分钟。PRA患者术后所需镇痛药物极少,静脉注射吗啡等效剂量的中位(IQR)为0(0 - 5)mg。中位(IQR)住院时间为1(1 - 1)天,8例(16.0%)患者当日出院。有4例并发症:1例嗜铬细胞瘤导致的血压波动、1例再次插管、1例自限性出血和1例暂时性肋下神经失用症。无转为开放手术或死亡病例。

结论

我们的结果支持先前发表的研究结果,即PRA是一种安全的手术方法,学习曲线相对较短,术后镇痛药物使用极少,住院时间短。

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