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基于意图的自闭症谱系障碍治疗:儿童等待名单对照研究的可喜结果。

Intention-based therapy for autism spectrum disorder: promising results of a wait-list control study in children.

机构信息

Private Practice, Dallas, TX.

Palo Alto University, Palo Alto, CA.

出版信息

Explore (NY). 2014 Jan-Feb;10(1):13-23. doi: 10.1016/j.explore.2013.10.005. Epub 2013 Oct 17.

DOI:10.1016/j.explore.2013.10.005
PMID:24439092
Abstract

BACKGROUND

Autism is a complex neurodevelopmental disability that usually manifests during the first three years of life and typically lasts throughout a person's lifetime. The purpose of this study is to investigate the efficacy of NeuroModulation Technique (NMT), a form of intention-based therapy, in improving functioning in children diagnosed with autism.

METHODS

A total of 18 children who met the study criteria were selected to participate. All children completed baseline measures. The children in the experimental group (n = 9) received two sessions a week of NMT for six weeks. Then, children in the wait-list control group (n = 9) received two sessions a week of NMT for six weeks. Primary efficacy outcome measures included the Pervasive Developmental Disorder Behavioral Inventory Autism Composite Index, the Aberrant Behavior Checklist-Community Total Score, and the Autism Treatment Evaluation Checklist Total Score. Our hypotheses were that children in both groups would show significant improvement over their respective baseline scores following NMT treatment, which would reflect an improvement in adaptive behaviors as well as a decrease in maladaptive behaviors.

RESULTS

Statistical analysis indicates a significant improvement in both the experimental and wait-list control group on all primary outcome measures following NMT treatment. The wait-list control group demonstrated no significant improvement on test measures over baseline scores during the wait period. No adverse reactions were reported.

CONCLUSIONS

These findings suggest that NMT is a promising intervention for autism that has the potential to produce a significant reduction in maladaptive behaviors and a significant increase in adaptive behaviors within a relatively short period of time.

摘要

背景

自闭症是一种复杂的神经发育障碍,通常在生命的头三年表现出来,并且通常会持续一生。本研究的目的是探讨神经调节技术(NMT)的疗效,NMT 是一种基于意图的治疗形式,在改善自闭症诊断儿童的功能方面的效果。

方法

共选择了 18 名符合研究标准的儿童参与。所有儿童均完成基线测量。实验组(n = 9)每周接受两次 NMT,共 6 周。然后,等待名单对照组(n = 9)每周接受两次 NMT,共 6 周。主要疗效指标包括广泛性发育障碍行为量表自闭症综合指数、异常行为检查表-社区总分和自闭症治疗评估检查表总分。我们的假设是,两组儿童在接受 NMT 治疗后,其各自的基线分数都会有显著提高,这反映了适应行为的改善和适应不良行为的减少。

结果

统计分析表明,实验组和等待名单对照组在接受 NMT 治疗后,所有主要疗效指标均有显著改善。等待名单对照组在等待期间,其测试指标与基线分数相比没有显著提高。没有报告不良反应。

结论

这些发现表明,NMT 是一种有前途的自闭症干预方法,有可能在相对较短的时间内显著减少适应不良行为,并显著增加适应行为。

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