Division of General and Thoracic Surgery, Children's Mercy Hospitals and Clinics, Kansas City, MO.
Division of General and Thoracic Surgery, Children's Mercy Hospitals and Clinics, Kansas City, MO.
J Am Coll Surg. 2014 Feb;218(2):157-62. doi: 10.1016/j.jamcollsurg.2013.10.012. Epub 2013 Oct 25.
The management of traumatic pancreatic transection remains controversial.
A multi-institutional review from 1995 to 2012 was conducted comparing operative with nonoperative management for grades II and III blunt pancreatic injuries in patients younger than 18 years.
Fourteen pediatric trauma centers participated, yielding 167 patients; 57 underwent distal pancreatectomy and 95 were managed nonoperatively. Fifteen patients treated with operative drain placement only were studied separately. Patients undergoing resection had a shorter time to goal oral feeds (7.8 ± 0.7 days vs 15.1 ± 2.5 days; p = 0.007) and a lower rate of pseudocyst formation (0% vs 18%; p = 0.001). Pseudocyst formation resulted in a greater need for endoscopic and interventional radiologic procedures (26% vs 2%; p = 0.002) in the nonoperative group, as well as a longer time to complete resolution (38.6 ± 6.4 days vs 22.6 ± 5.0 days; p = 0.05) compared with resection. When looking at those patients with clear evidence of main duct injury at presentation, those undergoing resection also had fewer complications (33% vs 61%; p = 0.05) and fewer total days in-hospital (12.6 ± 8.4 days vs 17.5 ± 9.7 days; p = 0.04) compared with nonoperative management.
In children with blunt pancreatic injury, distal pancreatectomy is superior to nonoperative management with more rapid resumption of diet, fewer repeat interventions, and a shorter period to complete resolution. When the main duct is involved, the benefits to operative resection also include lower morbidity and fewer days of hospitalization. Therefore, assessing the status of the pancreatic duct is paramount in determining management.
创伤性胰腺横断的处理仍存在争议。
对 1995 年至 2012 年期间的多机构回顾性研究,比较手术与非手术治疗年龄小于 18 岁的 II 级和 III 级钝性胰腺损伤患者。
14 家小儿创伤中心参与,共 167 例患者;57 例行胰体尾切除术,95 例行非手术治疗。另外单独研究了 15 例仅行手术引流的患者。接受切除术的患者达到目标口服喂养的时间更短(7.8 ± 0.7 天比 15.1 ± 2.5 天;p = 0.007),假性囊肿形成的发生率更低(0%比 18%;p = 0.001)。在非手术组中,假性囊肿形成导致更多需要内镜和介入放射学治疗(26%比 2%;p = 0.002),并且完全缓解的时间也更长(38.6 ± 6.4 天比 22.6 ± 5.0 天;p = 0.05)。与切除术相比,当观察到有明确主胰管损伤表现的患者时,接受切除术的患者并发症也更少(33%比 61%;p = 0.05),住院时间也更短(12.6 ± 8.4 天比 17.5 ± 9.7 天;p = 0.04)。
在儿童钝性胰腺损伤中,胰体尾切除术优于非手术治疗,饮食恢复更快,重复干预更少,完全缓解时间更短。当主胰管受累时,手术切除的益处还包括更低的发病率和更少的住院天数。因此,评估胰管的状态对于确定治疗方案至关重要。