Kobayashi K, Imazu Y, Kawabata M, Shohmori T
Department of Clinical Neurochemistry, Okayama University Medical School, Japan.
Acta Med Okayama. 1987 Aug;41(4):179-81. doi: 10.18926/AMO/31735.
Concentrations of homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were measured in human cerebrospinal fluid (CSF) following long-term storage at -20 degrees C for intervals of three to 60 months. No significant changes in HVA levels were detected in CSF stored for up to 60 months. On the other hand, 5-HIAA concentrations remained stable for up to 6 months, but decreased significantly in the specimens stored for longer time intervals. The results indicate that 5-HIAA should be determined within 6 months after CSF collection, while HVA determinations may be delayed.
在-20℃下长期储存3至60个月后，测定了人脑脊液（CSF）中高香草酸（HVA）和5-羟吲哚乙酸（5-HIAA）的浓度。在储存长达60个月的脑脊液中未检测到HVA水平有显著变化。另一方面，5-HIAA浓度在长达6个月内保持稳定，但在储存时间更长的标本中显著降低。结果表明，5-HIAA应在脑脊液采集后6个月内测定，而HVA的测定可以延迟。
