Vullo V, Mastroianni C M, Contini C, Cignarella L, Massetti A P, Falciano M, Paoletti F, Di Seri M
Istituto di Malattie Infettive dell'Università La Sapienza di Roma, III Cattedra di Malattie Infettive, Policlinico Umberto I, Italy.
Boll Ist Sieroter Milan. 1987;66(2):130-3.
Lipopolysaccharide (LPS) of Salmonella typhi has been analyzed by immunoblotting with pooled sera from typhoid patients. Pooled typhoid sera have recognized all the antigenic determinants of S. typhi LPS, giving a strong reaction with the repeating units on the O-side chains as well as with the core region. Cross-reacting antigens have been observed with the LPS of S. typhimurium and S. enteritidis, while no heterologous reactions were seen with the LPS of E. coli strains.
利用伤寒患者的混合血清通过免疫印迹法对伤寒沙门氏菌的脂多糖(LPS)进行了分析。混合伤寒血清识别出了伤寒沙门氏菌LPS的所有抗原决定簇,与O侧链上的重复单元以及核心区域产生了强烈反应。已观察到与鼠伤寒沙门氏菌和肠炎沙门氏菌的LPS存在交叉反应抗原,而与大肠杆菌菌株的LPS未观察到异源反应。