大肠杆菌O78 O抗原多糖的结构研究

Structural studies of the Escherichia coli O78 O-antigen polysaccharide.

作者信息

Jansson P E, Lindberg B, Widmalm G, Leontein K

机构信息

Department of Organic Chemistry, University of Stockholm, Sweden.

出版信息

Carbohydr Res. 1987 Jul 15;165(1):87-92. doi: 10.1016/0008-6215(87)80080-0.

DOI:10.1016/0008-6215(87)80080-0

PMID:2444338

Abstract

The structure of the O-antigen polysaccharide from Escherichia coli O78 has been investigated; methylation analysis, partial solvolysis with liquid hydrogen fluoride, and 2D-n.m.r. spectroscopy were the principal methods used. It is concluded that the polysaccharide is composed of tetrasaccharide repeating-units having the following structure.----3)-beta-D-GlcpNAc-(1----4)-beta-D-GlcpNAc- (1----4)-beta-D-Manp-(1----4)-alpha-D-Manp-(1----

摘要

对大肠杆菌O78的O抗原多糖结构进行了研究；主要采用的方法有甲基化分析、用液态氟化氢进行部分溶剂解以及二维核磁共振光谱法。得出的结论是，该多糖由具有以下结构的四糖重复单元组成。----3)-β-D-氨基葡萄糖-(1----4)-β-D-氨基葡萄糖-(1----4)-β-D-甘露糖-(1----4)-α-D-甘露糖-(1----