Engineering & Technology Research Center of Traditional Chinese Veterinary Medicine of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Key Laboratory of Animal Drug Project of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences, Lanzhou, P.R. China.
Engineering & Technology Research Center of Traditional Chinese Veterinary Medicine of Gansu Province, Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Key Laboratory of Animal Drug Project of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agricultural Sciences, Lanzhou, P.R. China.
Theriogenology. 2014 Mar 15;81(5):645-50. doi: 10.1016/j.theriogenology.2013.11.019. Epub 2013 Dec 18.
Sheng Hua Tang, a classical herbal formula consisting of Radix Angelicae sinensis, Ligustici rhizoma, Semen persicae, Zingiberis rhizoma, and Radix glycyrrhizae, is known to be beneficial in alleviating postpartum diseases and facilitating a return to normal reproductive function. This study investigated whether the administration of Sheng Hua Tang within 2 to 4 hours after delivery was effective as a preventive treatment for reducing the risk of retained placenta in Holstein dairy cows. A total of 357 cows, each of which had delivered its calf spontaneously, were randomly allocated to one of two groups. In the treatment group, the cows (n = 175) received Sheng Hua Tang with an oral dose of 0.36 g crude herb per kg·body weight once daily for three consecutive days. The controls (n = 182) received no treatment. The placental retention proportion was 4.0% and 17.0% within 12 hours after delivery in the treated and control animals, respectively (P < 0.01). We found decreases in the calving-to-first-service interval (73.2 ± 25.1 vs. 81.9 ± 32.8 days; P < 0.01), calving-to-conception interval (93.4 ± 38.8 vs. 114.6 ± 42.9 days; P < 0.01), and service per conception (1.5 ± 0.8 vs. 1.9 ± 1.0 days; P < 0.01) in the treatment group compared with the control group. The first artificial insemination conception proportion was higher in the treatment group than in the control group (60.4% vs. 41.1%; P = 0.01). Moreover, the between-group difference in the proportion of cows that were pregnant within 180 days postpartum approached statistical significance (88.2% vs. 80.6%; P = 0.07). Sheng Hua Tang showed beneficial effects in reducing the incidence of retained placenta and improving subsequent reproductive performance in cows. This preventive treatment strategy would be effective in improving the management of puerperal health. The potential benefits of Sheng Hua Tang warrant further investigation to determine whether this preventive treatment strategy can be endorsed as a general preventive approach in postpartum cows.
生化汤，一种由当归、川芎、桃仁、干姜和甘草组成的经典中草药配方，被认为有助于缓解产后疾病并促进正常生殖功能的恢复。本研究旨在探讨在产后 2 至 4 小时内给予生化汤是否可作为一种预防措施，以降低荷斯坦奶牛发生胎盘滞留的风险。共有 357 头自然分娩的奶牛，随机分为两组。在治疗组中，奶牛（n = 175）每天口服 0.36 g 生药/kg·体重，连续 3 天。对照组（n = 182）未接受治疗。产后 12 小时内，治疗组和对照组的胎盘滞留比例分别为 4.0%和 17.0%（P < 0.01）。我们发现，治疗组的产犊至首次配种间隔（73.2 ± 25.1 天 vs. 81.9 ± 32.8 天；P < 0.01）、产犊至受胎间隔（93.4 ± 38.8 天 vs. 114.6 ± 42.9 天；P < 0.01）和配种受胎率（1.5 ± 0.8 天 vs. 1.9 ± 1.0 天；P < 0.01）均低于对照组。与对照组相比，治疗组的首次人工授精受胎率更高（60.4% vs. 41.1%；P = 0.01）。此外，两组产后 180 天内怀孕的奶牛比例差异接近统计学意义（88.2% vs. 80.6%；P = 0.07）。生化汤在降低胎盘滞留发生率和改善奶牛后续繁殖性能方面显示出有益效果。这种预防治疗策略在改善产后健康管理方面可能具有有效性。生化汤的潜在益处值得进一步研究，以确定这种预防治疗策略是否可以作为产后奶牛的一般预防方法得到认可。
