十氯酮和灭蚁灵对小鼠对乙酰氨基酚急性肝毒性的影响。
Effect of chlordecone and mirex on the acute hepatotoxicity of acetaminophen in mice.
作者信息
Fouse B L, Hodgson E
机构信息
Toxicology Program, North Carolina State University, Raleigh 27695.
出版信息
Gen Pharmacol. 1987;18(6):623-30. doi: 10.1016/0306-3623(87)90035-8.
PMID:2444490
Abstract
- Acetaminophen toxicity, as measured by leakage of intracellular enzymes, was increased by chlordecone and mirex with mirex having the greater effect. 2. These effects were confirmed by histological examination and by studies of enzyme leakage from isolated hepatocytes.
摘要
- 以细胞内酶泄漏衡量的对乙酰氨基酚毒性，被开蓬和灭蚁灵增强，其中灭蚁灵的影响更大。2. 这些影响通过组织学检查以及对分离肝细胞的酶泄漏研究得到证实。
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