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用于控制凝血活酶时间值和校准凝血活酶的冻干血浆

[Lyophilized plasmas for the control of thromboplastin time values and calibration of thromboplastins].

作者信息

Sikorová J, Vorlová Z

机构信息

Institut für Hämatologie und Bluttransfusion Praha, CSSR.

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1987;114(3):423-8.

PMID:2444517
Abstract

The paper deals with the production of normal and pathological plasmas for the calibration of thromboplastin. Calibration is performed according to WHO principles. We compared single charges of thromboplastin (Sevac, CSSR, human brain) with each other and a selected reference charge with British thromboplastin. Lyophilised reference plasmas produced (20-50 healthy blood donors) and plasmas taken from patients treated with coumarin derivates (single and mixtures) could replace their fresh equivalents which was confirmed by testing 4 different batches. The stability of these plasmas (for a time of at least 12 months) was proved by repeated checks. These plasmas also served as controls in other laboratories in Czechoslovakia.

摘要

本文论述了用于凝血活酶校准的正常和病理血浆的制备。校准按照世界卫生组织的原则进行。我们将不同批次的凝血活酶(Sevac,捷克斯洛伐克社会主义共和国,人脑来源)相互比较,并将选定的参考批次与英国凝血活酶进行比较。所制备的冻干参考血浆(来自20 - 50名健康献血者)以及从接受香豆素衍生物治疗(单一或混合用药)的患者采集的血浆可以替代其新鲜等效物,这一点在对4个不同批次进行测试后得到了证实。通过反复检查证明了这些血浆的稳定性(至少12个月)。这些血浆还在捷克斯洛伐克的其他实验室用作对照。

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Folia Haematol Int Mag Klin Morphol Blutforsch. 1987;114(3):423-8.
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