海地太子港地震后霍乱和其他急性腹泻病因的重要性。
Importance of cholera and other etiologies of acute diarrhea in post-earthquake Port-au-Prince, Haiti.
机构信息
Les Centres GHESKIO, Port-au-Prince, Haiti; Division of Infectious Disease and International Health, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; Division of Infectious Diseases, Center for Global Health, Weill Cornell Medical College, New York, New York.
出版信息
Am J Trop Med Hyg. 2014 Mar;90(3):511-7. doi: 10.4269/ajtmh.13-0514. Epub 2014 Jan 20.
We estimated the proportion of diarrhea attributable to cholera and other pathogens during the rainy and dry seasons in patients seen in two urban health settings: a cholera treatment center (CTC) and oral rehydration points (ORPs). During April 1, 2011-November 30, 2012, stool samples were collected from 1,206 of 10,845 patients who came to the GHESKIO CTC or to the community ORPs with acute diarrhea, cultured for Vibrio cholerae, and tested by multiplex polymerase reaction. Vibrio cholerae was isolated from 409 (41.8%, 95% confidence interval [CI] = 38.7-44.9%) of the 979 specimens from the CTC and in 45 (19.8%, 95% CI = 14.8-25.6%) of the 227 specimens from the ORPs. Frequencies varied from 21.4% (95% CI = 16.6-26.7%) during the dry season to 46.8% (95% CI = 42.9-50.7%) in the rainy season. Shigella, enterotoxigenic Escherichia coli, rotavirus, and Cryptosporidium were frequent causes of diarrhea in children less than five years of age.
我们在两个城市卫生环境中（霍乱治疗中心和口服补液点）对就诊的患者进行了研究，以评估雨季和旱季中因霍乱和其他病原体导致的腹泻比例。2011 年 4 月 1 日至 2012 年 11 月 30 日，对来自 GHESKIO 霍乱治疗中心或社区口服补液点的 10845 例急性腹泻患者的 1206 例粪便样本进行了采集，对霍乱弧菌进行了培养，并采用多重聚合酶链反应进行了检测。从霍乱治疗中心的 979 个标本中分离出 409 株（41.8%，95%置信区间[CI] = 38.7-44.9%），从口服补液点的 227 个标本中分离出 45 株（19.8%，95% CI = 14.8-25.6%）。在旱季，这一比例从 21.4%（95% CI = 16.6-26.7%）到雨季的 46.8%（95% CI = 42.9-50.7%）不等。小于 5 岁的儿童中，志贺菌、肠产毒性大肠杆菌、轮状病毒和隐孢子虫是导致腹泻的常见病原体。
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