饮食蛋白质与血管生成。

Dietary proteins and angiogenesis.

机构信息

Department of Molecular and Biochemistry, University of Málaga, Málaga E-29071, Spain.

出版信息

Nutrients. 2014 Jan 17;6(1):371-81. doi: 10.3390/nu6010371.

DOI:10.3390/nu6010371

PMID:24445377

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3916867/

Abstract

Both defective and persistent angiogenesis are linked to pathological situations in the adult. Compounds able to modulate angiogenesis have a potential value for the treatment of such pathologies. Several small molecules present in the diet have been shown to have modulatory effects on angiogenesis. This review presents the current state of knowledge on the potential modulatory roles of dietary proteins on angiogenesis. There is currently limited available information on the topic. Milk contains at least three proteins for which modulatory effects on angiogenesis have been previously demonstrated. On the other hand, there is some scarce information on the potential of dietary lectins, edible plant proteins and high protein diets to modulate angiogenesis.

摘要

血管生成异常和持续性血管生成都与成年人的病理情况有关。能够调节血管生成的化合物对于治疗这些疾病具有潜在价值。饮食中的一些小分子已被证明对血管生成具有调节作用。本文综述了饮食蛋白对血管生成潜在调节作用的最新研究进展。目前，关于这一主题的信息有限。牛奶中至少含有三种先前已被证明具有血管生成调节作用的蛋白质。另一方面，关于饮食凝集素、食用植物蛋白和高蛋白饮食调节血管生成的潜力的信息也很少。