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[二尖瓣修复术与二尖瓣置换术]

[Mitral valve repair versus mitral valve replacement].

作者信息

Onnasch J F, Schneider F, Mierzwa M, Mohr F W

机构信息

Klinik für Herzchirurgie, Herzzentrum Universität Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany,

出版信息

Z Kardiol. 2001 Dec;90(Suppl 6):75-80. doi: 10.1007/s003920170012.

Abstract

Over the past 40 years mitral valve surgery has changed dramatically. After initial enthusiasm with the introduction of valve prostheses in the 1960s, a renewed interest in repair techniques began in the 1970s with the introduction of annuloplasty rings. These repair techniques revealed that the integrity of the subvalvular apparatus plays an important role in left ventricular function. When considering the major series comparing early and late results of mitral valve repair versus prosthetic mitral valve replacement, operative mortality rate is lower for patients with mitral valve repair. Long-term results also show a superior survival rate after mitral valve reconstruction. In addition, several problems can occur with the prosthetic valve, such as thromboembolism and endocarditis. All of these factors favor valve repair over replacement. The success of mitral valve repair depends on many factors: etiology of the mitral valve disease and the resultant pathomorphology of the valve, patient's circumstances such as age or contraindication for anticoagulation, and the experience of the surgeon. The decision whether to repair or replace the mitral valve depends on these factors. Data in the literature and in large collective databases reflect the advantages of mitral valve repair, with over 75 % of current mitral valve surgeries being repairs.In the past 5 years the exposure of the mitral valve through a right lateral minithoracotomy using video assistance has developed into a widespread technique. This approach allows complex mitral valve repair as well as mitral valve replacement even with biological stentless prostheses, with decreased morbidity. The addition of radiofrequency ablation for restoration of sinus rhythm enhances the outcome after mitral valve surgery, and can also be easily performed through a minithoracotomy technique.

摘要

在过去40年里,二尖瓣手术发生了巨大变化。20世纪60年代引入瓣膜假体后,人们最初热情高涨,而到了70年代,随着瓣环成形环的引入,对修复技术又重新产生了兴趣。这些修复技术表明,瓣下结构的完整性在左心室功能中起着重要作用。在比较二尖瓣修复与人工二尖瓣置换的早期和晚期结果的主要系列研究中,二尖瓣修复患者的手术死亡率较低。长期结果也显示二尖瓣重建后的生存率更高。此外,人工瓣膜会出现一些问题,如血栓栓塞和心内膜炎。所有这些因素都表明瓣膜修复优于瓣膜置换。二尖瓣修复的成功取决于许多因素:二尖瓣疾病的病因以及由此产生的瓣膜病理形态、患者情况,如年龄或抗凝禁忌证,以及外科医生的经验。决定修复还是置换二尖瓣取决于这些因素。文献和大型综合数据库中的数据反映了二尖瓣修复的优势,目前超过75%的二尖瓣手术是修复手术。在过去5年里,通过右侧小切口胸腔镜辅助暴露二尖瓣已发展成为一种广泛应用的技术。这种方法允许进行复杂的二尖瓣修复以及二尖瓣置换,甚至使用生物无支架假体,且发病率降低。增加射频消融以恢复窦性心律可提高二尖瓣手术后的疗效,并且也可通过小切口胸腔镜技术轻松完成。

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