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[活检材料中乳腺导管上皮细胞良性增殖的诊断]

[Diagnostics of benign ductal epithelial cell proliferation of the breast in biopsy material].

作者信息

Sinn H-P, Flechtenmacher C, Aulmann S

机构信息

Pathologisches Institut , Universität Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Deutschland,

出版信息

Pathologe. 2014 Feb;35(1):18-25. doi: 10.1007/s00292-013-1886-7.

DOI:10.1007/s00292-013-1886-7
PMID:24448666
Abstract

The pathological evaluation of radiological or sonographical abnormalities by needle core biopsy of the breast frequently involves the differential diagnosis of benign epithelial cell proliferations. The lesions to be considered include usual type and atypical ductal epithelial cell hyperplasia, columnar cell changes including flat epithelial cell atypia, the spectrum of hyperplastic and atypical apocrine epithelial cell proliferations and papillary lesions. This review provides an overview of the diagnostic criteria, the current terminology and the differential diagnosis of these lesions. The clinical management and the prognosis of the lesions are discussed.

摘要

通过乳腺针芯活检对影像学或超声检查异常进行病理评估,常常需要对良性上皮细胞增殖进行鉴别诊断。需要考虑的病变包括普通型和非典型导管上皮细胞增生、柱状细胞改变(包括扁平上皮细胞异型性)、增生性和非典型顶泌汗腺上皮细胞增殖谱以及乳头状病变。本综述概述了这些病变的诊断标准、当前术语和鉴别诊断。还讨论了这些病变的临床处理和预后。

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[Diagnostics of benign ductal epithelial cell proliferation of the breast in biopsy material].[活检材料中乳腺导管上皮细胞良性增殖的诊断]
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2
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本文引用的文献

1
Incidental atypical proliferative lesions in reduction mammoplasty specimens: analysis of 2498 cases from 2 tertiary women's health centers.在缩胸术标本中偶然发现的非典型增生性病变:来自 2 个三级妇女保健中心的 2498 例分析。
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Pure flat epithelial atypia: is there a place for routine surgery?单纯平坦上皮不典型增生:是否需要常规手术?
Diagn Interv Imaging. 2013 Sep;94(9):861-9. doi: 10.1016/j.diii.2013.01.011. Epub 2013 Mar 7.
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Flat ductal intraepithelial neoplasia 1A diagnosed at stereotactic core needle biopsy: is excisional biopsy indicated?
在立体定向核心针活检中诊断出的 1A 级扁平管内上皮内瘤变:是否需要进行切除术活检?
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Intraductal papillary lesions of the breast: clinical and pathological correlation.乳腺导管内乳头状病变:临床与病理相关性
Am Surg. 2012 Oct;78(10):1161-5.
5
Flat epithelial atypia with and without atypical ductal hyperplasia: to re-excise or not. Results of a 5-year prospective study.伴有和不伴有非典型导管增生的平坦上皮不典型:再次切除还是不切除。一项 5 年前瞻性研究的结果。
Virchows Arch. 2012 Oct;461(4):419-23. doi: 10.1007/s00428-012-1312-1. Epub 2012 Sep 8.
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Pathologic outcomes of nonmalignant papillary breast lesions diagnosed at imaging-guided core needle biopsy.影像学引导下核心针活检诊断为非恶性的乳头状乳腺病变的病理结果。
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7
Nonmalignant breast papillary lesions at core-needle biopsy: a meta-analysis of underestimation and influencing factors.核心针活检中的非恶性乳腺乳头状病变:低估的荟萃分析及影响因素。
Ann Surg Oncol. 2013 Jan;20(1):94-101. doi: 10.1245/s10434-012-2590-1. Epub 2012 Aug 10.
8
Early Breast Cancer Precursor Lesions: Lessons Learned from Molecular and Clinical Studies.早期乳腺癌前驱病变:分子与临床研究的经验教训
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9
The radial scar of the breast diagnosed at core needle biopsy.经粗针活检诊断的乳腺放射状瘢痕。
Proc (Bayl Univ Med Cent). 2012 Jan;25(1):3-5. doi: 10.1080/08998280.2012.11928768.
10
Long term follow-up and risk of breast cancer after a radial scar or complex sclerosing lesion has been identified in a benign open breast biopsy.良性开放性乳腺活检中发现放射状瘢痕或复杂硬化性病变后乳腺癌的长期随访和风险。
Eur J Surg Oncol. 2011 Aug;37(8):709-13. doi: 10.1016/j.ejso.2011.04.011.