Sinn H-P, Flechtenmacher C, Aulmann S
Pathologisches Institut , Universität Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Deutschland,
Pathologe. 2014 Feb;35(1):18-25. doi: 10.1007/s00292-013-1886-7.
The pathological evaluation of radiological or sonographical abnormalities by needle core biopsy of the breast frequently involves the differential diagnosis of benign epithelial cell proliferations. The lesions to be considered include usual type and atypical ductal epithelial cell hyperplasia, columnar cell changes including flat epithelial cell atypia, the spectrum of hyperplastic and atypical apocrine epithelial cell proliferations and papillary lesions. This review provides an overview of the diagnostic criteria, the current terminology and the differential diagnosis of these lesions. The clinical management and the prognosis of the lesions are discussed.
通过乳腺针芯活检对影像学或超声检查异常进行病理评估,常常需要对良性上皮细胞增殖进行鉴别诊断。需要考虑的病变包括普通型和非典型导管上皮细胞增生、柱状细胞改变(包括扁平上皮细胞异型性)、增生性和非典型顶泌汗腺上皮细胞增殖谱以及乳头状病变。本综述概述了这些病变的诊断标准、当前术语和鉴别诊断。还讨论了这些病变的临床处理和预后。