Department of Electronics and Systems, University of A Coruña, 15071 A Coruña and Department of Biochemistry, Genetics and Immunology, University of Vigo, 36201 Vigo, Spain.
Bioinformatics. 2014 May 1;30(9):1310-1. doi: 10.1093/bioinformatics/btu032. Epub 2014 Jan 21.
The selection of models of nucleotide substitution is one of the major steps of modern phylogenetic analysis. Different tools exist to accomplish this task, among which jModelTest 2 (jMT2) is one of the most popular. Still, to deal with large DNA alignments with hundreds or thousands of loci, users of jMT2 need to have access to High Performance Computing clusters, including installation and configuration capabilities, conditions not always met. Here we present jmodeltest.org, a novel web server for the transparent execution of jMT2 across different platforms and for a wide range of users. Its main benefit is straightforward execution, avoiding any configuration/execution issues, and reducing significantly in most cases the time required to complete the analysis.
核苷酸替代模型的选择是现代系统发育分析的主要步骤之一。有不同的工具可以完成这项任务，其中 jModelTest 2（jMT2）是最受欢迎的工具之一。但是，对于处理具有数百或数千个基因座的大型 DNA 比对，jMT2 的用户需要访问高性能计算集群，包括安装和配置能力，而这些条件并不总是满足的。在这里，我们介绍了 jmodeltest.org，这是一个新的网络服务器，用于在不同的平台上透明地执行 jMT2，并为广泛的用户提供服务。它的主要优点是执行简单，避免了任何配置/执行问题，并在大多数情况下大大减少了完成分析所需的时间。
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