Allum W H, Mack P, Priestman T J, Fielding J W
Queen Elizabeth Hospital, Birmingham.
Ann R Coll Surg Engl. 1987 Sep;69(5):220-1.
Eighteen patients with local recurrence of colorectal cancer have been treated by external beam radiotherapy for pain relief. Seven received a fractionated course of 4500cGy and the remainder received single fractions of 1000cGy, a number being treated more than once. The median survival for all patients once recurrence had produced pain was 7 months. Treatment benefit was recorded in 71% treated by fractionated courses and in 66% by single fractions. The duration of pain relief was 3 months for each method. The repeatability of single fraction treatment indicates that this is a worthwhile alternative technique, particularly for those in poor general condition.
18例局部复发性结直肠癌患者接受了体外放射治疗以缓解疼痛。7例接受了4500cGy的分次放疗疗程,其余患者接受了1000cGy的单次放疗,部分患者接受了多次治疗。所有患者一旦复发出现疼痛,其中位生存期为7个月。分次放疗疗程治疗的患者中有71%记录到治疗获益,单次放疗的患者中有66%记录到治疗获益。两种方法的疼痛缓解持续时间均为3个月。单次放疗的可重复性表明这是一种值得采用的替代技术,尤其适用于一般状况较差的患者。