Suppr超能文献

糖尿病患儿的角膜生物力学特征

Corneal biomechanical characteristics in children with diabetes mellitus.

作者信息

Nalcacioglu-Yuksekkaya Pınar, Sen Emine, Cetinkaya Semra, Bas Veysel, Aycan Zehra, Ozturk Faruk

机构信息

Department of Pediatric Opthalmology, Dr Sami Ulus Children's Health and Disease Training and Research Hospital, Babur Street No: 44, Altindag, Ankara, 06080, Turkey,

出版信息

Int Ophthalmol. 2014 Aug;34(4):881-6. doi: 10.1007/s10792-014-9899-7. Epub 2014 Jan 23.

Abstract

To compare the corneal biomechanical properties in children with type 1 diabetes mellitus (DM) and healthy children. In this cross-sectional study, the study and control groups were composed of 68 children with DM and 74 healthy children, respectively. The corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg) and corneal-compensated intraocular pressure (IOPcc) were measured with the ocular response analyzer (ORA). Associations between ocular and diabetic parameters were also evaluated. There were no statistically significant differences between the two groups in age or gender distribution. The mean CH was 10.8 ± 1.5 and 10.7 ± 1.7 mmHg while the mean CRF was 10.9 ± 1.9 and 10.5 ± 1.6 mmHg in the diabetic group and control group, respectively. The mean IOPg was 15.9 ± 3.7 and 15.2 ± 3.4 mmHg, and the mean IOPcc was 15.8 ± 3.0 and 15.3 ± 3.4 mmHg in the diabetic and control group, respectively. There were no statistically significant differences between the two groups for CH, CRF, IOPg, and IOPcc measurements (independent t test, p = 0.624, p = 0.207, p = 0.263, p = 0.395, respectively). This study shows that type 1 DM does not have any effect on the corneal biomechanical parameters in childhood.

摘要

比较1型糖尿病(DM)患儿与健康儿童的角膜生物力学特性。在这项横断面研究中,研究组和对照组分别由68名DM患儿和74名健康儿童组成。使用眼反应分析仪(ORA)测量角膜滞后(CH)、角膜阻力因子(CRF)、Goldmann相关眼压(IOPg)和角膜补偿眼压(IOPcc)。还评估了眼部参数与糖尿病参数之间的关联。两组在年龄或性别分布上无统计学显著差异。糖尿病组和对照组的平均CH分别为10.8±1.5和10.7±1.7 mmHg,而平均CRF分别为10.9±1.9和10.5±1.6 mmHg。糖尿病组和对照组的平均IOPg分别为15.9±3.7和15.2±3.4 mmHg,平均IOPcc分别为15.8±3.0和15.3±3.4 mmHg。两组在CH、CRF、IOPg和IOPcc测量值方面无统计学显著差异(独立t检验,p分别为0.624、0.207、0.263、0.395)。本研究表明,1型DM对儿童期角膜生物力学参数无任何影响。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验