Wang Jinfeng, Liu Minjie, Liu Chao, Ye Yun, Huang Guanhong
Department of Radiation Oncology, The Affiliated Lianyungang Hospital of Bengbu Medical College, Jiangsu, China.
J Radiat Res. 2014 May;55(3):559-67. doi: 10.1093/jrr/rrt144. Epub 2014 Jan 22.
There are two main enteral feeding strategies-namely nasogastric (NG) tube feeding and percutaneous gastrostomy-used to improve the nutritional status of patients with head and neck cancer (HNC). But up till now there has been no consistent evidence about which method of enteral feeding is the optimal method for this patient group. To compare the effectiveness of percutaneous gastrostomy and NGT feeding in patients with HNC, relevant literature was identified through Medline, Embase, Pubmed, Cochrane, Wiley and manual searches. We included randomized controlled trials (RCTs) and non-experimental studies comparing percutaneous gastrostomy-including percutaneous endoscopic gastrostomy (PEG) and percutaneous fluoroscopic gastrostomy (PFG) -with NG for HNC patients. Data extraction recorded characteristics of intervention, type of study and factors that contributed to the methodological quality of the individual studies. Data were then compared with respect to nutritional status, duration of feeding, complications, radiotherapy delays, disease-free survival and overall survival. Methodological quality of RCTs and non-experimental studies were assessed with separate standard grading scales. It became apparent from our studies that both feeding strategies have advantages and disadvantages.
有两种主要的肠内喂养策略，即鼻胃管喂养和经皮胃造瘘术，用于改善头颈癌（HNC）患者的营养状况。但到目前为止，对于该患者群体哪种肠内喂养方法是最佳方法，尚无一致的证据。为比较经皮胃造瘘术和鼻胃管喂养在头颈癌患者中的有效性，通过医学文献数据库（Medline）、荷兰医学文摘数据库（Embase）、美国国立医学图书馆医学期刊数据库（Pubmed）、考克兰图书馆（Cochrane）、威利数据库（Wiley）及手工检索确定了相关文献。我们纳入了比较经皮胃造瘘术（包括经皮内镜下胃造瘘术（PEG）和经皮透视下胃造瘘术（PFG））与鼻胃管用于头颈癌患者的随机对照试验（RCT）和非实验性研究。数据提取记录了干预措施的特征、研究类型以及影响各研究方法学质量的因素。然后就营养状况、喂养持续时间、并发症、放疗延迟、无病生存期和总生存期对数据进行比较。采用单独的标准分级量表评估随机对照试验和非实验性研究的方法学质量。我们的研究表明，两种喂养策略都有优缺点。
