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直肠癌保括约肌手术:来自克什米尔地区的单中心研究

Sphincter-saving surgeries for rectal cancer: A single center study from Kashmir.

作者信息

Mir Shabeer Ahmed, Chowdri Nisar A, Parray Fazl Q, Mir Parvez Ahmed, Bashir Yasir, Nafae Muntakhab

机构信息

Department of General and Minimal Access Surgery, Colorectal Division, Sheri Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Department of Otorhinolaryngology, SMHS Hospital, Srinagar, Jammu and Kashmir, India.

出版信息

South Asian J Cancer. 2013 Oct;2(4):227-31. doi: 10.4103/2278-330X.119929.

Abstract

SUMMARY AND BACKGROUND DATA

The goals in the treatment of rectal cancer are cure, local control, and preservation of sphincter, bladder and sexual function. Surgical resection using sharp mesorectal dissection is important for achieving these goals.

OBJECTIVES

The current treatment of choice for carcinoma rectum is sphincter saving procedures, which have practically replaced the previously done abdominoperineal resection. We performed a study in our institute to evaluate the surgical outcome and complications of rectal cancer.

MATERIALS AND METHODS

This prospectivestudy included 117 patients, treated for primary rectal cancer by low anterior resection (LAR) from May 2007 to December 2010. All patients underwent standard total mesorectal excision (TME) followed by restoration of continuity.

RESULTS

The peri-operative mortality rate was 2.5% (3/117). Post-operative complications occurred in 32% of the patients. After a median follow up of 42 months, local recurrences developed in 6 (5%) patients and distant metastasis in 5 (4.2%). The survival rate was 93%.

CONCLUSION

The concept of total mesorectal excision (TME), advances in stapling technology and neoadjuvant therapy have made it possible to preserve the anal sphincter in most of the patients. Rectal cancer needs to be managed especially in a specialized unit for better results.

摘要

摘要与背景数据

直肠癌治疗的目标是治愈、局部控制以及保留括约肌、膀胱和性功能。采用锐性直肠系膜切除术进行手术切除对于实现这些目标至关重要。

目的

目前直肠癌的首选治疗方法是保留括约肌的手术,实际上已取代了先前进行的腹会阴联合切除术。我们在本机构开展了一项研究,以评估直肠癌的手术结果及并发症。

材料与方法

这项前瞻性研究纳入了2007年5月至2010年12月期间因原发性直肠癌接受低位前切除术(LAR)治疗的117例患者。所有患者均接受了标准的全直肠系膜切除术(TME),随后恢复肠道连续性。

结果

围手术期死亡率为2.5%(3/117)。32%的患者出现术后并发症。中位随访42个月后,6例(5%)患者发生局部复发,5例(4.2%)患者发生远处转移。生存率为93%。

结论

全直肠系膜切除术(TME)的理念、吻合器技术的进步以及新辅助治疗使得大多数患者能够保留肛门括约肌。直肠癌尤其需要在专科单位进行治疗以获得更好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc80/3889046/a2e68fb599ce/SAJC-2-227-g001.jpg

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