Hospital Israelita Albert Einstein, Universidade Federal de S ão Paulo, SP, Brazil and Wake Forest University, NC, USA.
Int Braz J Urol. 2013 Nov-Dec;39(6):841-6. doi: 10.1590/S1677-5538.IBJU.2013.06.10.
The aim of this study was to assess the uroflowmetry data in a large population of asymptomatic Brazilian men submitted to a health check up program and their correlation to IPSS and prostate size.
Asymptomatic men underwent a health check-up program between January and December 2012. The inclusion criteria were men between 40 and 70 years, IPSS ≤ 7, without bladder, prostate, urethral surgery, neurological diseases, urinary tract infection, PSA < 4.0 ng/dL and urinary volume higher than 150 mL. Urological assessment consisted of clinical history, IPSS, digital rectal examination (DRE), prostate specific antigen (PSA), urinalysis, ultrasonography and uroflowmetry.
A total of 1041 asymptomatic men were included in this study. The average age was 49 years and average maximum flow rate was 17.4 mL/s. In spite of IPSS and prostate size increase with aging, they had a weak correlation with Qmax cutoffs (10 mL/s and 15 mL/s). A total of 85 men (8.3%) had more than 60 years, and even in this group, Qmax was higher than 15 mL/s. Out of 1041 men, 117 had IPSS less than 8 and Qmax less than 10 mL/s.
In asymptomatic men there is a weak correlation between IPSS, prostate size and uroflowmetric data. The establishment of different normal cutoffs seems to be complicated and uroflowmetry data should be interpreted with caution in order to avoid misdiagnosis.
本研究旨在评估大量无症状巴西男性在健康检查计划中的尿流率数据及其与 IPSS 和前列腺大小的相关性。
无症状男性于 2012 年 1 月至 12 月期间接受健康检查计划。纳入标准为 40 至 70 岁之间的男性,IPSS≤7,无膀胱、前列腺、尿道手术、神经疾病、尿路感染、PSA<4.0ng/dL 和尿量>150mL。泌尿科评估包括临床病史、IPSS、直肠指检(DRE)、前列腺特异性抗原(PSA)、尿液分析、超声检查和尿流率。
本研究共纳入 1041 名无症状男性。平均年龄为 49 岁,平均最大尿流率为 17.4mL/s。尽管 IPSS 和前列腺体积随年龄增长而增加,但它们与 Qmax 截断值(10mL/s 和 15mL/s)相关性较弱。共有 85 名男性(8.3%)年龄超过 60 岁,即使在这个年龄组中,Qmax 也高于 15mL/s。在 1041 名男性中,有 117 名 IPSS 小于 8 且 Qmax 小于 10mL/s。
在无症状男性中,IPSS、前列腺体积和尿流率数据之间相关性较弱。建立不同的正常截断值似乎很复杂,为了避免误诊,应谨慎解释尿流率数据。