Suppr超能文献

血管内修复治疗钝性创伤性主动脉损伤患者的结果。

Outcomes of endovascular repair for patients with blunt traumatic aortic injury.

机构信息

From the Department of Cardiothoracic and Vascular Surgery, University of Texas Medical School at Houston, Houston, Texas.

出版信息

J Trauma Acute Care Surg. 2014 Feb;76(2):510-6. doi: 10.1097/TA.0b013e3182aafe8c.

Abstract

BACKGROUND

Traumatic aortic injury (TAI) remains a leading cause of death after blunt force. Thoracic endovascular aortic repair (TEVAR) has been widely adopted as an alternative to open repair for the treatment of TAI. Although significant short-term benefits have been demonstrated for patients undergoing TEVAR, longer-term follow-up data are lacking.

METHODS

Trauma registry data were analyzed. Follow-up data were gathered from a combination of medical records, imaging, telephone interviews, and Social Security Death Index. Primary outcomes were in-hospital mortality, stroke, and paraplegia. Secondary outcomes included device-related adverse events (rupture, migration, or endoleak), secondary procedures, open conversion, and all-cause mortality.

RESULTS

Between September 2005 and July 2012, 82 consecutive patients (57 males, mean [SD] age, 39.5 [20] years; mean [SD] Injury Severity Score [ISS], 34 [9.5]) underwent TEVAR for TAI. A total of 87 devices were implanted: TAG (n = 36), CTAG (n = 12) (WL Gore, Flagstaff, AZ); Talent (n = 29), Valiant (n = 5) (Medtronic, Santa Rosa, CA); TX2 (n = 2) (Cook, Bloomington, IN); and other (n = 3). Left subclavian artery coverage was required in 32 patients (39%). Technical success rate was 100%. Rates of in-hospital mortality, stroke, and paraplegia were 5.0%, 2.4%, and 0%, respectively.Median follow-up time was 2.3 years (range, 0-7 years). The availability of follow-up data was as follows: Social Security Death Index (100%), telephone interview (68%), clinic visit (61%), and imaging (82%). The incidence of device-related adverse events was 2.4%. There were four secondary procedures: two patients underwent a carotid-subclavian bypass, and two had an open conversion for device-related complications. Survival was 95% at 30 days, 88% at 1 year, 87% at 2 years, and 82% at 5 years.

CONCLUSION

At midterm follow-up, TEVAR is an effective and durable option for the treatment of TAI in properly selected patients. Device-related adverse events, secondary procedures, and open conversion are rare. Follow-up remains a challenge.

LEVEL OF EVIDENCE

Therapeutic study, level V.

摘要

背景

创伤性主动脉损伤(TAI)仍然是钝性外伤后的主要死亡原因。胸主动脉腔内修复术(TEVAR)已广泛应用于 TAI 的治疗,替代开放修复。尽管接受 TEVAR 的患者显示出显著的短期益处,但缺乏长期随访数据。

方法

分析创伤登记数据。通过病历、影像学检查、电话访谈和社会保障死亡指数相结合来收集随访数据。主要结局是院内死亡率、卒中和截瘫。次要结局包括器械相关不良事件(破裂、移位或内漏)、二次手术、开放转换和全因死亡率。

结果

2005 年 9 月至 2012 年 7 月,82 例连续患者(57 例男性,平均[标准差]年龄 39.5[20]岁;平均[标准差]损伤严重度评分[ISS] 34[9.5])因 TAI 接受 TEVAR 治疗。共植入 87 个器械:TAG(n=36)、CTAG(n=12)(WL Gore,Flagstaff,AZ);Talent(n=29)、Valiant(n=5)(美敦力,圣拉扎罗,CA);TX2(n=2)(库克,布鲁明顿,IN);以及其他(n=3)。32 例(39%)需要覆盖左锁骨下动脉。技术成功率为 100%。院内死亡率、卒中和截瘫的发生率分别为 5.0%、2.4%和 0%。中位随访时间为 2.3 年(0-7 年)。随访数据的获得情况如下:社会保障死亡指数(100%)、电话访谈(68%)、门诊就诊(61%)和影像学检查(82%)。器械相关不良事件的发生率为 2.4%。有 4 例二次手术:2 例患者行颈动脉-锁骨下旁路术,2 例因器械相关并发症行开放转换。30 天存活率为 95%,1 年存活率为 88%,2 年存活率为 87%,5 年存活率为 82%。

结论

在中期随访中,TEVAR 是一种有效且持久的选择,适用于适当选择的 TAI 患者。器械相关不良事件、二次手术和开放转换很少见。随访仍然是一个挑战。

证据水平

治疗研究,5 级。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验