Institute for Biomaterials and Biomedical Engineering, University of Toronto, 164 College St., Toronto, ON, M5S 3E1, Canada.
Adv Mater. 2014 May;26(18):2838-43. doi: 10.1002/adma.201305168. Epub 2014 Jan 23.
The first example of so-called "digital microfluidics" (DMF) implemented on paper by inkjet printing is reported. A sandwich enzyme-linked immunosorbent assay (ELISA) is demonstrated as an example of a complex, multistep protocol that would be difficult to achieve with capillary-driven paper microfluidics. Furthermore, it is shown that paper-based DMF devices have comparable performance to traditional photolithographically patterned DMF devices at a fraction of the cost.
首次在纸张上通过喷墨打印实现了所谓的“数字微流控（DMF）”。夹心酶联免疫吸附测定（ELISA）被证明是一个复杂的、多步骤的方案的范例，这对于基于毛细作用的纸张微流控来说是难以实现的。此外，研究表明，纸基 DMF 器件的性能可与传统的光刻图案化 DMF 器件相媲美，而成本却只有其一小部分。
