Department of Biochemistry and Molecular Biology, Federal University of Viçosa, 36570-000 Viçosa, MG, Brazil.
Department of Chemistry, Federal University of Minas Gerais, 31270-901 Belo Horizonte, MG, Brazil.
Evid Based Complement Alternat Med. 2013;2013:480509. doi: 10.1155/2013/480509. Epub 2013 Dec 29.
The bioassay-guided isolation of the active extract of Salvinia auriculata Aubl. led to the separation of three main compounds, characterized as stigmasterone, stigmasterol, and friedelinol. The pure form of diketosteroid presented a potential antibacterial activity with a minimum inhibitory concentration (MIC) value of 0.01 mg mL(-1) against Staphylococcus aureus isolated from animals with mastitis infections. The active extract also showed a similar result to that previously obtained with pure diketosteroid when tested with the same isolates. The present study's results demonstrate the potential of this plant as an excipient for the production of antibacterial soaps aimed at controlling bovine mastitis infections, especially on small farms.
生物测定法指导下从水龙骨科水龙骨中分离出三种主要化合物，分别为豆甾酮、豆甾醇和表扶甾醇。二酮甾醇的纯物质表现出潜在的抗菌活性，对从乳腺炎感染动物中分离出的金黄色葡萄球菌的最小抑菌浓度 (MIC) 值为 0.01mg/mL(-1)。活性提取物在与相同分离物进行测试时，也表现出与纯二酮甾醇相似的结果。本研究结果表明，这种植物作为生产抗菌肥皂的赋形剂具有潜力，可用于控制牛乳腺炎感染，特别是在小型农场。
