Allelic imbalance associated with the schizophrenia risk SNP rs1344706 indicates a cis-acting variant in ZNF804A.
作者信息
Guella Ilaria, Vawter Marquis P
机构信息
Functional Genomics Laboratory, Department of Psychiatry and Human Behavior, University of California, Irvine, CA, United States.
Functional Genomics Laboratory, Department of Psychiatry and Human Behavior, University of California, Irvine, CA, United States.
出版信息
Schizophr Res. 2014 Mar;153(1-3):243-5. doi: 10.1016/j.schres.2014.01.005. Epub 2014 Jan 23.
Abstract
摘要
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本文引用的文献
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Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex.人类背外侧前额叶皮层中精神分裂症易感基因 ZNF804A 的等位基因失衡证据。
Schizophr Res. 2014 Jan;152(1):111-6. doi: 10.1016/j.schres.2013.11.021. Epub 2013 Dec 7.
2
ZNF804A and cortical structure in schizophrenia: in vivo and postmortem studies.ZNF804A 与精神分裂症的皮质结构：体内和尸检研究。
Schizophr Bull. 2014 May;40(3):532-41. doi: 10.1093/schbul/sbt123. Epub 2013 Sep 27.
3
Potential Impact of miR-137 and Its Targets in Schizophrenia.miR-137 及其靶标在精神分裂症中的潜在影响。
Front Genet. 2013 Apr 26;4:58. doi: 10.3389/fgene.2013.00058. eCollection 2013.
4
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.五种主要精神疾病具有共同影响的风险基因座的鉴定：全基因组分析。
Lancet. 2013 Apr 20;381(9875):1371-1379. doi: 10.1016/S0140-6736(12)62129-1. Epub 2013 Feb 28.
5
The regulation of gene expression involved in TGF-β signaling by ZNF804A, a risk gene for schizophrenia.锌指蛋白 804A 调控 TGF-β 信号通路相关基因表达，锌指蛋白 804A 是精神分裂症的风险基因。
Schizophr Res. 2013 May;146(1-3):273-8. doi: 10.1016/j.schres.2013.01.026. Epub 2013 Feb 22.
6
Evidence that schizophrenia risk variation in the ZNF804A gene exerts its effects during fetal brain development.有证据表明，ZNF804A 基因的精神分裂症风险变异在胎儿大脑发育过程中发挥作用。
Am J Psychiatry. 2012 Dec;169(12):1301-8. doi: 10.1176/appi.ajp.2012.11121845.
7
Expression analysis of a novel mRNA variant of the schizophrenia risk gene ZNF804A.精神分裂症风险基因ZNF804A的一种新型mRNA变体的表达分析
Schizophr Res. 2012 Nov;141(2-3):277-8. doi: 10.1016/j.schres.2012.08.015. Epub 2012 Sep 23.
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Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137.实验验证候选精神分裂症基因 ZNF804A 是 hsa-miR-137 的作用靶点。
Schizophr Res. 2012 Oct;141(1):60-64. doi: 10.1016/j.schres.2012.06.038. Epub 2012 Aug 9.
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Schizophr Res. 2012 Oct;141(1):40-7. doi: 10.1016/j.schres.2012.07.013. Epub 2012 Aug 5.
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ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2.锌指蛋白 804a 调控精神分裂症相关基因 PRSS16、COMT、PDE4B 和 DRD2 的表达。
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