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在克里特岛引入热带利什曼原虫MON-58会导致这种罕见酶株的定居和传播吗?

Will the introduction of Leishmania tropica MON-58, in the island of Crete, lead to the settlement and spread of this rare zymodeme?

作者信息

Ntais Pantelis, Christodoulou Vasiliki, Tsirigotakis Nikolaos, Dokianakis Emmanouil, Dedet Jean-Pierre, Pratlong Francine, Antoniou Maria

机构信息

Laboratory of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, Faculty of Medicine, University of Crete, Crete, Greece.

Laboratory of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, Faculty of Medicine, University of Crete, Crete, Greece; Veterinary Services of Cyprus, Nicosia, Cyprus.

出版信息

Acta Trop. 2014 Apr;132:125-30. doi: 10.1016/j.actatropica.2014.01.003. Epub 2014 Jan 24.

DOI:10.1016/j.actatropica.2014.01.003
PMID:24462941
Abstract

The rare zymodeme, Leishmania tropica MON-58, was isolated from a young Afghan refugee with a facial cutaneous lesion who had come to live in Crete early 2008. The same zymodeme variant was isolated from a local dog that had never travelled outside the island, with symptoms of visceral leishmaniasis, which stayed in the area where the patient worked during the summer months. This is the first record of L. tropica in a host, other than human, in Greece and another example of introduction of a vector borne pathogen in a focus where local vector/s can sustain it, with the risk of initiation of new transmission cycle/s.

摘要

罕见的酶谱型,热带利什曼原虫MON - 58,是从一名患有面部皮肤损伤的年轻阿富汗难民身上分离出来的,该难民于2008年初来到克里特岛居住。从一只从未离开过该岛的当地狗身上也分离出了相同的酶谱型变体,这只狗有内脏利什曼病的症状,在夏季停留在患者工作的区域。这是希腊除人类以外宿主中热带利什曼原虫的首次记录,也是病媒传播病原体在当地病媒能够维持其传播的疫源地引入的又一实例,存在引发新传播循环的风险。

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