Department of Integrative Physiology and Anatomy, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX, 76107, USA,
Eur J Appl Physiol. 2014 Mar;114(3):579-86. doi: 10.1007/s00421-014-2823-z. Epub 2014 Jan 28.
While the importance of regulating arterial blood pressure within a 'normal' range is widely appreciated, the definition of 'normal' and the means by which humans and other species regulate blood pressure under various conditions remain hotly debated. The effects of diverse physiological, pathological and environmental challenges on blood pressure and the mechanisms that attempt to maintain it at an optimal level are reviewed and critically analyzed in a series of articles published in this themed issue of the European Journal of Applied Physiology. We summarize here the major points made in these reviews, with emphasis on unifying concepts of regulatory mechanisms and future directions for research.
虽然将动脉血压调节在“正常”范围内的重要性已被广泛认识,但“正常”的定义以及人类和其他物种在各种条件下调节血压的方式仍存在激烈争议。在本期《欧洲应用生理学杂志》特刊中发表的一系列文章中,我们对各种生理、病理和环境挑战对血压的影响以及试图将血压维持在最佳水平的机制进行了综述和批判性分析。在这里,我们总结了这些综述中的主要观点,重点是调节机制的统一概念和未来的研究方向。