Bollschweiler E, Baltin C, Berlth F, Mönig S P, Hölscher A H
Klinik und Poliklinik für Allgemein, Viszeral- und Tumorchirurgie, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland,
Chirurg. 2014 Mar;85(3):203-7. doi: 10.1007/s00104-013-2602-0.
Quality of life (QOL) is becoming more and more relevant in clinical research. An increasing number of publications each year confirmed this. The aim of this review is to summarize current data of QOL after surgical procedures. The results are represented by two examples each of malignant and benign diseases. The evaluation of QOL for patients with cancer is only possible with respect to the prognosis. Prospective randomized trials comparing laparoscopic and open surgery for early gastric cancer are only available from Asia. Data from the USA show that the QOL after gastrectomy was worse regardless of the surgical procedure. During the next 6 months the QOL improved but about one third of the patients had severe impairment during longer follow-up periods. Patients with R1 resection of pancreatic cancer showed only a slightly better prognosis but significantly better QOL compared to patients without resection. The results for the various procedures of cholecystectomy or hernia repair are not always consistent.
生活质量（QOL）在临床研究中变得越来越重要。每年越来越多的出版物证实了这一点。本综述的目的是总结外科手术后生活质量的当前数据。结果通过恶性和良性疾病各两个例子来呈现。对于癌症患者，只有在考虑预后的情况下才有可能评估生活质量。比较早期胃癌腹腔镜手术和开放手术的前瞻性随机试验仅来自亚洲。美国的数据表明，无论手术方式如何，胃切除术后的生活质量都较差。在接下来的6个月里，生活质量有所改善，但约三分之一的患者在更长的随访期内有严重损害。与未切除的患者相比，胰腺癌R1切除患者的预后仅略好，但生活质量明显更好。胆囊切除术或疝气修补术的各种手术结果并不总是一致的。
