Department of Pediatrics, BaYi Children's Hospital Affiliated to the Clinical Medical College of the General Hospital of Beijing Military Region, Southern Medical University, Beijing, China.
World J Pediatr. 2014 Feb;10(1):53-8. doi: 10.1007/s12519-013-0445-x. Epub 2014 Jan 25.
Information about clinical outcomes of very preterm (VPT) infants in tertiary neonatal intensive care unit (NICU) setting is scant in China. This study aimed to investigate the mortality and morbidity of VPT infants admitted to BaYi Children's Hospital, which serves as a NICU referral center for the city of Beijing, China.
Retrospectively collected perinatal/neonatal data on all admissions of infants born at <32 weeks of gestational age and subsequently admitted to the VPTNICU from clinical records between October 2010 and September 2011.
Totally 729 infants were identified. 90% of VPT infants were outborn. The overall survival of the infants to discharge was 92%, which increased with increasing gestational age (range from 69% at <28 weeks to 99% at 31 weeks). The incidence of bronchopulmonary dysplasia was 4%, retinopathy of prematurity requiring treatment 2%, intraventricular hemorrhage III-IV 6%, and periventricular leukomalacia 2%. 10% of the VPT infants had a major morbidity at discharge.
The outcomes of the VTP infants at this referral NICU were comparable to those in tertiary centers in developed countries. The most common complications were lower than those in other cohorts. Accordingly, high-volume NICU may minimize the adverse effects of VPT infants' transport.
在中国，三级新生儿重症监护病房（NICU）中极早产儿（VPT）的临床结局信息很少。本研究旨在调查作为北京市新生儿重症监护病房转诊中心的八一儿童医院收治的 VPT 婴儿的死亡率和发病率。
从 2010 年 10 月至 2011 年 9 月的临床记录中，回顾性地收集所有胎龄<32 周并随后被收入 VPTNICU 的新生儿的围产期/新生儿数据。
共确定了 729 名婴儿。90%的 VPT 婴儿为外院出生。婴儿出院时的总存活率为 92%，随着胎龄的增加而增加（范围从<28 周的 69%到 31 周的 99%）。支气管肺发育不良的发生率为 4%，需要治疗的早产儿视网膜病变为 2%，III-IV 级脑室内出血为 6%，脑室周围白质软化为 2%。10%的 VPT 婴儿出院时有主要并发症。
该转诊 NICU 的 VTP 婴儿的结局与发达国家的三级中心相当。最常见的并发症低于其他队列。因此，大容量 NICU 可能会最小化 VPT 婴儿转运的不良影响。
