Torres Tiago, Alexandre José Manuel, Mendonça Denisa, Vasconcelos Carlos, Silva Berta Martins, Selores Manuela
Serviço de Dermatologia, Centro Hospitalar do Porto, Edifício das Consultas ExternasEx-CICAP, Rua D. Manuel II, s/n, 4100, Porto, Portugal,
Am J Clin Dermatol. 2014 Apr;15(2):129-35. doi: 10.1007/s40257-014-0061-0.
Psoriasis is a chronic inflammatory disease associated with increased cardiovascular mortality, secondary to the increased prevalence of cardiovascular risk factors and premature atherosclerosis. Physical activity is a vital component in prevention and management of cardiovascular disease. Few studies have examined the level of physical activity in psoriasis patients, using validated questionnaires or other objective assessment tools.
The aim of this study was to analyze and compare physical activity undertaken by patients with severe psoriasis and healthy controls, using the International Physical Activity Questionnaire-Short Form (IPAQ-S), a validated instrument for assessing physical activity.
Ninety patients with severe plaque-type psoriasis and 160 healthy subjects were enrolled in the present study. Physical activity was evaluated using IPAQ-S.
Psoriasis patients had reduced levels of physical activity compared with non-psoriasis patients, regardless of sex or whether the variable was continuous or categorical. The odds ratio for low-level physical activity for psoriasis patients, compared with controls, was 3.42 (95% CI 1.47-7.91), indicating that this severe psoriasis population did not undertake recommended levels of physical activity.
Psoriasis patients exhibit decreased levels of physical activity, possibly for both psychological and physiological reasons. The lack of physical activity may contribute to the increased risk of cardiovascular disease in psoriasis patients, in addition to the intrinsic risks related to systemic inflammation and psoriasis-linked comorbidities. Regular physical activity should be encouraged in all psoriasis patients because of its beneficial effects on systemic inflammation and cardiometabolic comorbidities associated with psoriasis.
银屑病是一种慢性炎症性疾病，由于心血管危险因素患病率增加和过早发生动脉粥样硬化，其心血管死亡率也随之升高。体育活动是预防和管理心血管疾病的重要组成部分。很少有研究使用经过验证的问卷或其他客观评估工具来检测银屑病患者的体育活动水平。
本研究旨在使用国际体力活动问卷简表（IPAQ-S）这一经过验证的评估体力活动的工具，分析和比较重度银屑病患者和健康对照者的体力活动情况。
本研究纳入了90例重度斑块型银屑病患者和160例健康受试者。使用IPAQ-S评估体力活动情况。
无论性别如何，也无论变量是连续变量还是分类变量，银屑病患者的体力活动水平均低于非银屑病患者。与对照组相比，银屑病患者低水平体力活动的优势比为3.42（95%置信区间1.47-7.91），这表明该重度银屑病人群未达到推荐的体力活动水平。
银屑病患者的体力活动水平降低，可能是由于心理和生理两方面的原因。除了与全身炎症和银屑病相关合并症有关的内在风险外，体力活动不足可能会增加银屑病患者患心血管疾病的风险。鉴于规律的体力活动对与银屑病相关的全身炎症和心血管代谢合并症具有有益作用，应鼓励所有银屑病患者进行规律的体力活动。
