van Dommelen Paula, de Kroon Marlou L A, Cameron Noël, Schönbeck Yvonne, van Buuren Stef
Department of Life Style, TNO, Leiden, The Netherlands.
Department of Public and Occupational Health, Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands.
PLoS One. 2014 Jan 22;9(1):e85769. doi: 10.1371/journal.pone.0085769. eCollection 2014.
It is known that height and body mass index (BMI) are correlated in childhood. However, its impact on the (trend of) national prevalence rates of overweight and obesity has never been investigated. The aim of our study is to investigate the relation between height and national prevalence rates of overweight and obesity in childhood between 1980, 1997, and 2009, and to calculate which fixed value of p (2.0,2.1, …,3.0) in kg/m(p) during childhood is most accurate in predicting adult overweight.
Cross-sectional growth data of children from three Dutch nationwide surveys in 1980, 1997, and 2009, and longitudinal data from the Terneuzen Birth Cohort and the Harpenden Growth Study were used. Relative risks (RR) and 95% confidence intervals (CI) were calculated. Our study showed that tall (>1 standard deviation (SD)) girls aged 5.0-13.9 y were more often overweight (RR = 3.5,95%CI:2.8-4.4) and obese (RR = 3.9,95%CI:2.1-7.4) than short girls (<-1 SD). Similar results were found in boys aged 5.0-14.9 y (RR = 4.4,95%CI:3.4-5.7 and RR = 5.3,95%CI:2.6-11.0). No large differences were found in the other age groups and in comparison with children with an average stature. Tall boys aged 2.0-4.9 y had a significantly higher positive trend in overweight between 1980 and 1997 compared to short boys (RR = 4.0,95%CI:1.38-11.9). For other age groups and in girls, no significant trends were found. The optimal Area Under the Curve (AUC) to predict adult overweight was found for p = 2.0.
Tall girls aged 5.0-13.9y and tall boys aged 5.0-14.9y have much higher prevalence rates of overweight and obesity than their shorter peers. We suggest taking into account the impact of height when evaluating trends and variations of BMI distributions in childhood, and to use BMI to predict adult overweight.
已知身高与儿童期的体重指数（BMI）相关。然而，其对全国超重和肥胖患病率（趋势）的影响从未被研究过。我们研究的目的是调查1980年、1997年和2009年儿童期身高与全国超重和肥胖患病率之间的关系，并计算儿童期以千克/米（p）为单位的哪个固定值p（2.0、2.1、…、3.0）在预测成人超重方面最为准确。
使用了来自荷兰1980年、1997年和2009年三次全国性调查的儿童横断面生长数据，以及特尔讷曾出生队列和哈彭登生长研究的纵向数据。计算了相对风险（RR）和95%置信区间（CI）。我们的研究表明，5.0 - 13.9岁的高个子（>1标准差（SD））女孩比矮个子（<-1 SD）女孩更常超重（RR = 3.5，95%CI：2.8 - 4.4）和肥胖（RR = 3.9，95%CI：2.1 - 7.4）。在5.0 - 14.9岁的男孩中也发现了类似结果（RR = 4.4，95%CI：3.4 - 5.7和RR = 5.3，95%CI：2.6 - 11.0）。在其他年龄组以及与平均身高的儿童相比时未发现大的差异。与矮个子男孩相比，1980年至1997年期间2.0 - 4.9岁的高个子男孩超重的正向趋势显著更高（RR = 4.0，95%CI：1.38 - 11.9）。对于其他年龄组和女孩，未发现显著趋势。发现预测成人超重的最佳曲线下面积（AUC）对应p = 2.0。
5.0 - 13.9岁的高个子女孩和5.0 - 14.9岁的高个子男孩超重和肥胖的患病率远高于他们较矮的同龄人。我们建议在评估儿童期BMI分布的趋势和变化时考虑身高的影响，并使用BMI来预测成人超重。
