Sugawara Norio, Yasui-Furukori Norio, Yamazaki Manabu, Shimoda Kazutaka, Mori Takao, Sugai Takuro, Suzuki Yutaro, Someya Toshiyuki
Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki, Japan ; Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan.
Japan Psychiatric Hospitals Association, Tokyo, Japan.
PLoS One. 2014 Jan 23;9(1):e86826. doi: 10.1371/journal.pone.0086826. eCollection 2014.
There is growing concern about the metabolic abnormalities in patients with schizophrenia.
The aim of this study was to assess the attitudes of psychiatrists toward metabolic adverse events in patients with schizophrenia.
A BRIEF QUESTIONNAIRE WAS CONSTRUCTED TO COVER THE FOLLOWING BROAD AREAS: the psychiatrists' recognition of the metabolic risk of antipsychotic therapy, pattern of monitoring patients for physical risks, practice pattern for physical risks, and knowledge of metabolic disturbance. In March 2012, the questionnaire was mailed to 8,482 psychiatrists who were working at hospitals belonging to the Japan Psychiatric Hospitals Association.
The overall response rate was 2,583/8,482 (30.5%). Of the respondents, 85.2% (2,200/2,581) reported that they were concerned about prescribing antipsychotics that have a risk of elevating blood sugar; 47.6% (1,201/2,524) stated that their frequency of monitoring patients under antipsychotic treatment was based on their own experiences; and only 20.6% (5,22/2,534) of respondents answered that the frequency with which they monitored their patients was sufficient to reduce the metabolic risks.
Psychiatrists practicing in Japan were generally aware and concerned about the metabolic risks for patients being treated with antipsychotics. Although psychiatrists should monitor their patients for metabolic abnormalities to balance these risks, a limited number of psychiatrists answered that the frequency with which they monitored patients to reduce the metabolic risks was sufficient. Promotion of the best practices of pharmacotherapy and monitoring is needed for psychiatrists treating patients with schizophrenia.
精神分裂症患者的代谢异常问题日益受到关注。
本研究旨在评估精神科医生对精神分裂症患者代谢不良事件的态度。
构建了一份简短问卷,涵盖以下广泛领域:精神科医生对抗精神病药物治疗代谢风险的认识、对患者身体风险的监测模式、身体风险的实践模式以及对代谢紊乱的了解。2012年3月,该问卷被邮寄给在日本精神病医院协会所属医院工作的8482名精神科医生。
总体回复率为2583/8482(30.5%)。在受访者中,85.2%(2200/2581)报告称他们担心开具具有升高血糖风险的抗精神病药物;47.6%(1201/2524)表示他们对抗精神病药物治疗患者的监测频率基于自身经验;只有20.6%(522/2534)的受访者回答他们对患者的监测频率足以降低代谢风险。
在日本执业的精神科医生普遍意识到并关注接受抗精神病药物治疗患者的代谢风险。尽管精神科医生应监测患者的代谢异常以平衡这些风险,但只有少数精神科医生回答他们为降低代谢风险而对患者的监测频率足够。对于治疗精神分裂症患者的精神科医生而言,需要推广药物治疗和监测的最佳实践。