Gomółka Ewa, Kapala Małgorzata, Hydzik Piotr
Pracownia Toksykologii Analitycznej i Terapii Monitorowanej, Katedra Toksykologii i Chorób Srodowiskowych, Uniwersytet Jagielloński Collegium Medium, Kraków.
Zakład Diagnostyki Laboratoryjnej, Instytut Medycyny Pracy i Zdrowia, Srodowiskowego w Sosnowcu.
Przegl Lek. 2013;70(8):506-10.
The purpose of the research was to present the number of ethylene glycol and methanol poisonings in south Poland in the years 2010-2012, based on data from toxicological laboratories in Kraków and Sosnowiec. Total numbers of positive determinations of the toxic alcohols were 380-ethylene glycol and 152-methanol. Most of the patients poisoned with the toxic alcohols were men (87.4%), the mean age of the patients was 48.1 years. Mean ethylene glycol concentration in samples from poisoned patients was 57.5 mg/dl in serum and 286.2 mg/dl in urine; mean blood methanol concentration was 1.4 g/l. Samples collected from poisoned patients treated on the area of whole voivodeship were determined in toxicology laboratories. According to information about orderers of ethylene glycol and methanol tests, positive results of the toxic alcohols were the most often in big cities and in cities, where department of toxicology were located (Kraków and Sosnowiec). In many cases patients were treated in hospitals in small cities, and samples collected from patients were transported to perform toxicological determination. The study shows, that intoxications with ethylene glycol and methanol are a big problem in Poland and the number of methanol poisonings markedly increased in the years 2010-2012.
该研究的目的是基于克拉科夫和索斯诺维茨毒理学实验室的数据,呈现2010 - 2012年波兰南部乙二醇和甲醇中毒的病例数量。有毒醇类阳性检测总数为:乙二醇380例,甲醇152例。大多数有毒醇类中毒患者为男性(87.4%),患者平均年龄为48.1岁。中毒患者样本中乙二醇的平均浓度在血清中为57.5毫克/分升,在尿液中为286.2毫克/分升;血液中甲醇平均浓度为1.4克/升。从整个省接受治疗的中毒患者采集的样本在毒理学实验室进行检测。根据乙二醇和甲醇检测委托方的信息,有毒醇类的阳性结果在大城市以及设有毒理学部门的城市(克拉科夫和索斯诺维茨)最为常见。在许多情况下,患者在小城市的医院接受治疗,从患者身上采集的样本被送去进行毒理学检测。该研究表明,乙二醇和甲醇中毒在波兰是一个严重问题,且2010 - 2012年甲醇中毒病例数量显著增加。