Zajac Maciej, Andrzejczyk Agata, Kuich Aleksandra, Tyrańska-Fobke Anna, Waldman Wojciech, Sein Anand Jacek
Zakład Toksykologii Klinicznej, Gdański Uniwersytet Medyczny.
Zakład Zdrowia Publicznego i Medycyny Spolecznej, Gdański Uniwersytet Medyczny.
Przegl Lek. 2013;70(8):525-7.
In the last decade we have observed a considerable increase in nonmedical usage of dextromethorphan (DXM) among young age groups, especially school children between 13 and 16 yrs. We analysed the "trip reports" after use of DXM, available on a website: www.hyperreal.info in the years 1999-2013. The data collected by authors were analysed according to: age, sex, symptoms, dose of DXM, a reason and a place of using the drug. A review of 124 "trip reports" showed that the majority of their writers are male (M 90.3%, F 9.7%). Young people, aged 16-20 (80.4%), dominated among the study population. The most common place of using DXM was a flat of a drug user (70.2%), and the reason of using a willingness to experiment with new psychoactive substances (41.9%) as well as the desire of "get high" (25.8%). The majority of users used DXM at least once again in their lives (56.5%). A single dose of the ingested drug ranged from 120 mg to 1575 mg (mean 539.25 mg). Most often received doses were 450 mg (30.4%), 300 mg (12%), 900 mg (11.2%). DXM was positively assessed by the internauts as a recreational psychoactive substance (84.7%). The most common clinical symptoms described by internauts were: difficulties with walking (74.2%), visual illusions (73.4%), altered sense of time (41.9%), feeling of exteriorisation (35.5%), euphoria (33.1%), nausea and vomiting (32.3%), auditory illusions (30.6%) and pruritus (29.8%).
在过去十年中,我们观察到右美沙芬(DXM)在年轻人群体,尤其是13至16岁的学童中的非医疗用途显著增加。我们分析了1999年至2013年期间在网站www.hyperreal.info上可获取的使用DXM后的“旅行报告”。作者收集的数据根据年龄、性别、症状、DXM剂量、用药原因和用药地点进行了分析。对124份“旅行报告”的审查显示,大多数作者为男性(男性占90.3%,女性占9.7%)。16至20岁的年轻人(占80.4%)在研究人群中占主导地位。使用DXM最常见的地点是吸毒者的公寓(占70.2%),用药原因是尝试新的精神活性物质的意愿(占41.9%)以及“兴奋”的欲望(占25.8%)。大多数使用者一生中至少再次使用过一次DXM(占56.5%)。单次摄入药物的剂量范围为120毫克至1575毫克(平均539.25毫克)。最常摄入的剂量是450毫克(占30.4%)、300毫克(占12%)、900毫克(占11.2%)。DXM被网民积极评价为一种娱乐性精神活性物质(占84.7%)。网民描述的最常见临床症状为:行走困难(占74.2%)、视幻觉(占73.4%)、时间感改变(占41.9%)、超脱感(占35.5%)、欣快感(占33.1%)、恶心和呕吐(占32.3%)、听幻觉(占30.6%)和瘙痒(占29.8%)。