Van Dorsselaer A, Nebhi R, Sorokine O, Schindler P, Luu B
Laboratoire de Chimie organique des Substances naturelles, U.A., C.N.R.S. n. 31, Strasbourg.
C R Acad Sci III. 1987;305(14):555-60.
By studying highly purified CNS proteolipids, we have shown that DM-20 proteolipid, which was considered, until now, to be a minor brain proteolipid is, in fact, almost as abundant as the Major Myelin Proteolipid known also as Proteolipid Protein (PLP). DM-20 proteolipid is even the major brain proteolipid in young foetuses. It is only during myelinisation that the "Proteolipid Protein" increases rapidly and becomes equivalent in weight to DM-20 proteolipid. This study raises the question of the particular function of DM-20 proteolipid.
