高压氧疗法在促进急性伤口愈合方面是否有效：系统评价。
Does hyperbaric oxygen therapy work in facilitating acute wound healing: a systematic review.
机构信息
Dallas, Texas From the Department of Plastic Surgery, University of Texas Southwestern Medical Center.
出版信息
Plast Reconstr Surg. 2014 Feb;133(2):208e-215e. doi: 10.1097/01.prs.0000436849.79161.a4.
BACKGROUND
Adjunctive hyperbaric oxygen therapy is a safe and effective modality with which to increase tissue oxygenation and aid in healing of difficult wounds. The majority of the literature surrounding hyperbaric oxygen therapy supports its use in chronic wounds, but its use in acute wounds, flaps, and grafts is less well supported.
METHODS
The authors reviewed the Ovid, PubMed, and Cochrane Library databases, and selected studies, level III and above, using hyperbaric oxygen therapy in the treatment of complicated acute wounds, flaps, and grafts.
RESULTS
A total of eight studies were found to meet criteria for evaluation of adjunctive hyperbaric oxygen therapy in the treatment of complicated acute wounds, flaps, and grafts.
CONCLUSIONS
When combined with standard wound management principles, hyperbaric oxygen therapy can augment healing in complicated acute wounds. However, it is not indicated in normal wound management. Further investigation is required before it can be recommended as a mainstay in adjuvant wound therapy.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II.
背景
辅助高压氧疗法是一种安全有效的方法，可增加组织氧合并有助于治疗困难的伤口。大多数关于高压氧治疗的文献都支持其用于慢性伤口，但在急性伤口、皮瓣和移植物中的应用支持较少。
方法
作者检索了 Ovid、PubMed 和 Cochrane Library 数据库，并选择了使用高压氧治疗复杂急性伤口、皮瓣和移植物的 III 级及以上的研究。
结果
共有 8 项研究符合评估辅助高压氧治疗复杂急性伤口、皮瓣和移植物的标准。
结论
当与标准伤口管理原则结合使用时，高压氧治疗可以促进复杂急性伤口的愈合。然而，在正常的伤口管理中并不适用。在推荐其作为辅助伤口治疗的主要方法之前，需要进一步的研究。
临床问题/证据水平：治疗性，II 级。
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