Meredith Steven E, Robinson Andrew, Erb Philip, Spieler Claire A, Klugman Noah, Dutta Prabal, Dallery Jesse
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD;
Nicotine Tob Res. 2014 Jun;16(6):766-73. doi: 10.1093/ntr/ntt275. Epub 2014 Jan 27.
Mobile phones hold considerable promise for delivering evidence-based smoking cessation interventions that require frequent and objective assessment of smoking status via breath carbon monoxide (Breath CO) measurement. However, there are currently no commercially available mobile-phone-based Breath CO meters. We developed a mobile-phone-based Breath CO meter prototype that attaches to and communicates with a smartphone through an audio port. We then evaluated the reliability and the validity of Breath CO measures collected with the mobile meter prototype and assessed the usability and acceptability of the meter.
Participants included 20 regular smokers (≥10 cigarettes/day), 20 light smokers (<10 cigarettes/day), and 20 nonsmokers. Expired air samples were collected 4 times from each participant: twice with the mobile meter and twice with a commercially available Breath CO meter.
Measures calculated by the mobile meter correlated strongly with measures calculated by the commercial meter (r = .96, p < .001). Additionally, the mobile meter accurately distinguished between smokers and nonsmokers. The area under the receiver-operating characteristic curve for the mobile meter was 94.7%, and the meter had a combined sensitivity and specificity of 1.86 at an abstinence threshold of ≤6 ppm. Responses on an acceptability survey indicated that smokers liked the meter and would be interested in using it during a quit attempt.
The results of our study suggest that a mobile-phone-based Breath CO meter is a reliable, valid, and acceptable device for distinguishing between smokers and nonsmokers.
手机在提供基于证据的戒烟干预措施方面具有巨大潜力,这些干预措施需要通过测量呼出气体中的一氧化碳(呼出气一氧化碳)来频繁且客观地评估吸烟状况。然而,目前尚无市售的基于手机的呼出气一氧化碳测量仪。我们开发了一种基于手机的呼出气一氧化碳测量仪原型,它通过音频端口连接到智能手机并与之通信。然后,我们评估了使用该移动测量仪原型收集的呼出气一氧化碳测量值的可靠性和有效性,并评估了该测量仪的可用性和可接受性。
参与者包括20名经常吸烟者(每天≥10支香烟)、20名轻度吸烟者(每天<10支香烟)和20名非吸烟者。从每位参与者收集4次呼出气体样本:两次使用移动测量仪,两次使用市售的呼出气一氧化碳测量仪。
移动测量仪计算出的测量值与商用测量仪计算出的测量值高度相关(r = 0.96,p < 0.001)。此外,移动测量仪能够准确区分吸烟者和非吸烟者。移动测量仪的受试者工作特征曲线下面积为94.7%,在戒断阈值≤6 ppm时,该测量仪的综合灵敏度和特异性为1.86。可接受性调查的结果表明,吸烟者喜欢该测量仪,并对在戒烟尝试期间使用它感兴趣。
我们的研究结果表明,基于手机的呼出气一氧化碳测量仪是一种可靠、有效且可接受的区分吸烟者和非吸烟者的设备。