Bennet L, Groop L, Lindblad U, Agardh C D, Franks P W
Department of Clinical Sciences, Lund University, Malmö, Sweden; Family Medicine, Lund University, Malmö, Sweden.
Department of Clinical Sciences, Lund University, Malmö, Sweden; Department of Diabetes and Endocrinology/Lund Diabetes Centre, Skåne University Hospital, Malmö, Sweden.
Prim Care Diabetes. 2014 Oct;8(3):231-8. doi: 10.1016/j.pcd.2014.01.002. Epub 2014 Jan 25.
This study sought to compare type 2 diabetes (T2D) risk indicators in Iraqi immigrants with those in ethnic Swedes living in southern Sweden.
Population-based, cross-sectional cohort study of men and women, aged 30-75 years, born in Iraq or Sweden conducted in 2010-2012 in Malmö, Sweden. A 75g oral glucose tolerance test was performed and sociodemographic and lifestyle data were collected. T2D risk was assessed by the Finnish Diabetes Risk Score (FINDRISC).
In Iraqi versus Swedish participants, T2D was twice as prevalent (11.6 vs. 5.8%, p<0.001). A large proportion of the excess T2D risk was attributable to larger waist circumference and first-degree family history of diabetes. However, Iraqi ethnicity was a risk factor for T2D independently of other FINDRISC factors (odds ratio (OR) 2.5, 95% CI 1.6-3.9). The FINDRISC algorithm predicted that more Iraqis than Swedes (16.2 vs. 12.3%, p<0.001) will develop T2D within the next decade. The total annual costs for excess T2D risk in Iraqis are estimated to exceed 2.3 million euros in 2005, not accounting for worse quality of life.
Our study suggests that Middle Eastern ethnicity should be considered an independent risk indicator for diabetes. Accordingly, the implementation of culturally tailored prevention programs may be warranted.
本研究旨在比较伊拉克移民与居住在瑞典南部的瑞典族裔人群的2型糖尿病(T2D)风险指标。
2010 - 2012年在瑞典马尔默对30 - 75岁出生于伊拉克或瑞典的男性和女性进行基于人群的横断面队列研究。进行了75克口服葡萄糖耐量试验,并收集了社会人口学和生活方式数据。通过芬兰糖尿病风险评分(FINDRISC)评估T2D风险。
与瑞典参与者相比,伊拉克参与者中T2D的患病率是其两倍(11.6%对5.8%,p<0.001)。T2D风险增加的很大一部分归因于腰围较大和糖尿病一级家族史。然而,伊拉克族裔是T2D的一个风险因素,独立于其他FINDRISC因素(比值比(OR)2.5,95%置信区间1.6 - 3.9)。FINDRISC算法预测,未来十年内患T2D的伊拉克人将比瑞典人更多(16.2%对12.3%,p<0.001)。2005年伊拉克人T2D风险增加的年度总成本估计超过230万欧元,未考虑生活质量下降的情况。
我们的研究表明,中东族裔应被视为糖尿病的一个独立风险指标。因此,可能有必要实施针对不同文化背景的预防项目。