de Almeida Luiza Helena Silva, Leonardo Natália Gomes e Silva, Gomes Ana Paula Neutzling, Giardino Luciano, Souza Erick Miranda, Pappen Fernanda Geraldo
Department of Semiology and Clinics, School of Dentistry, UNIPel - Federal University of Pelotas, PelotasRS, Brazil.
Department of Endodontics, School of Dentistry, University of Torino, Italy.
Braz Dent J. 2013 Sep-Oct;24(5):477-81. doi: 10.1590/0103-6440201302041.
This study evaluated the influence of the addition of cetrimide and polypropylene glycol to sodium hypochlorite (NaOCl) on its capacity to dissolve pulp tissue. Bovine pulp fragments with standardized weight and volume were immersed for 5, 15 and 30 min in 2 mL of NaOCl and Hypoclean (NaOCl added with cetrimide and polypropylene glycol) solutions at 5.25%, 2.5%, 1%, 0.5% and 0.25% and afterwards re-weighted. Distilled water was used as a control. The percentage of tissue loss was considered for statistical analysis (univariate ANOVA, SPSS, v. 17.0) at 5% significance level. There was no tissue dissolution in the control group. NaOCl added with surfactants (Hypoclean) dissolved more pulp tissue (p<0.05) than NaOCl alone. Tissue dissolution was directly dependent on the concentration of solutions (p<0.05), and also on the time range (p<0.05). The combination of NaOCl at high and low concentrations with the surfactants cetrimide and polypropylene glycol increased significantly its capacity to dissolve pulp tissue.
本研究评估了在次氯酸钠（NaOCl）中添加西曲溴铵和聚丙二醇对其溶解牙髓组织能力的影响。将具有标准化重量和体积的牛牙髓碎片分别在5.25%、2.5%、1%、0.5%和0.25%的2 mL NaOCl溶液以及Hypoclean（添加了西曲溴铵和聚丙二醇的NaOCl）溶液中浸泡5分钟、15分钟和30分钟，之后重新称重。以蒸馏水作为对照。在5%的显著性水平下，采用单因素方差分析（SPSS，v. 17.0）对组织损失百分比进行统计分析。对照组未出现组织溶解现象。添加了表面活性剂（Hypoclean）的NaOCl比单独的NaOCl溶解更多的牙髓组织（p<0.05）。组织溶解直接取决于溶液浓度（p<0.05），也取决于时间范围（p<0.05）。高浓度和低浓度的NaOCl与表面活性剂西曲溴铵和聚丙二醇的组合显著提高了其溶解牙髓组织的能力。
