Department of Endodontics, Faculty of Dentistry, Selcuk University, Konya, Turkey.
J Endod. 2010 Feb;36(2):272-4. doi: 10.1016/j.joen.2009.10.027.
The organic tissue dissolution properties of irrigating solutions are important for the success of endodontic treatment. Chlorine dioxide (ClO2) has been recently proposed as an irrigation solution in endodontics. The organic tissue dissolution property of sodium hypochlorite (NaOCl) is well-known and extensively investigated, but apparently no data have been published on tissue-dissolving properties of ClO2. The aim of this in vitro study was to compare organic tissue dissolution capacity of NaOCl and ClO2. In this study, 5.25% NaOCl, 13.8% ClO2, and, as a control, isotonic saline solutions (0.9% NaCl) were used. Thirty bovine pulp specimens were previously weighed and immersed for 20 minutes in each test solution (changing the solution every 2 minutes). The pulp specimens were then blotted dry and weighed again. The percentage of weight loss was calculated and statistically analyzed by using one-way analysis of variance and post hoc Tukey honestly significant difference tests. Saline solution did not dissolve the organic tissue. Both 5.25% NaOCl and 13.8% ClO2 dissolved the tissue pieces more effectively than saline control (P < .05). No statistically significant difference was found between the tissue-dissolving properties of 5.25% NaOCl and those of 13.8% ClO2 (P > .05). Within the limitations of this in vitro study, it was concluded that ClO2 and NaOCl are equally efficient for dissolving organic tissue.
冲洗液的有机组织溶解特性对于牙髓治疗的成功至关重要。二氧化氯（ClO2）最近已被提议作为牙髓冲洗液。次氯酸钠（NaOCl）的有机组织溶解特性是众所周知的，并进行了广泛的研究，但显然没有关于 ClO2 的组织溶解特性的数据。本体外研究的目的是比较 NaOCl 和 ClO2 的有机组织溶解能力。在这项研究中，使用了 5.25%的 NaOCl、13.8%的 ClO2 以及作为对照的等渗生理盐水（0.9%的 NaCl）。30 个牛牙髓样本事先称重，然后在每种测试溶液中浸泡 20 分钟（每 2 分钟更换一次溶液）。然后将牙髓样本吸干并再次称重。计算重量损失的百分比，并通过单向方差分析和事后 Tukey 诚实显著差异检验进行统计学分析。生理盐水没有溶解有机组织。5.25%的 NaOCl 和 13.8%的 ClO2 都比生理盐水对照更有效地溶解组织碎片（P <.05）。5.25%的 NaOCl 和 13.8%的 ClO2 的组织溶解特性之间没有发现统计学上的显著差异（P >.05）。在本体外研究的限制范围内，得出结论，ClO2 和 NaOCl 对于溶解有机组织同样有效。
