Grasso Angelica Anna Chiara, Blanco Salvatore, Fantini Gemma, Torelli Fabrizio, Grasso Marco
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milano - Italy.
Urologia. 2014 Apr-Jun;81(2):115-9. doi: 10.5301/urologia.5000036. Epub 2013 Nov 28.
Recent findings reported an inverse relationship between solar ultraviolet-B (UV-B) exposure and mortality from various types of cancers, including renal cancer.
We reviewed the literature concerning the relationship between sun exposure and incidence of kidney cancer. We performed a case-control study, evaluating recreational sun exposure in 50 kidney cancer patients and 50 controls.A questionnaire concerning sun exposure habits during childhood, adult life and in the previous 2 years was filled in by every patient. The questionnaire focused on: hours/day spent in the sun during summer; hours/day spent sunbathing (considering as well which kind of UV protection was used); sunburns; holidays in tropical countries.
We found and analyzed few articles concerning the relationship between kidney cancer and sunlight exposure. The two cohorts of patients we evaluated were homogeneous for age, phototype, origin and living area.We found no statistically significant differences between sun exposure in patients affected by kidney cancer and controls, both during childhood and adult life; no differences were found in the use of sunscreens either.
Recreational sunlight exposure does not differ in our cohorts of patients and controls; studies on greater cohorts are needed to evaluate the effect of recreational sun exposure in the development of kidney cancer.
最近的研究结果表明，太阳紫外线B（UV-B）暴露与包括肾癌在内的各种癌症的死亡率之间存在负相关关系。
我们回顾了有关阳光暴露与肾癌发病率之间关系的文献。我们进行了一项病例对照研究，评估了50名肾癌患者和50名对照者的休闲性阳光暴露情况。每位患者都填写了一份关于童年、成年期以及过去两年阳光暴露习惯的问卷。问卷重点关注：夏季每天在阳光下度过的时间；每天晒太阳的时间（同时考虑使用的紫外线防护类型）；晒伤情况；在热带国家度假的情况。
我们发现并分析了少量关于肾癌与阳光暴露关系的文章。我们评估的两组患者在年龄、肤色类型、籍贯和居住地区方面具有同质性。我们发现，无论是在童年还是成年期，肾癌患者与对照者的阳光暴露情况均无统计学上的显著差异；在防晒霜的使用方面也未发现差异。
在我们的患者组和对照组中，休闲性阳光暴露情况没有差异；需要对更大规模的人群进行研究，以评估休闲性阳光暴露在肾癌发生发展中的作用。
