Boccato P, Briani G, d'Atri C, Pasini L, Blandamura S, Bizzaro N
Department of Pathology, Civil Hospital, San Doná di Piave, Italy.
Acta Cytol. 1988 Jan-Feb;32(1):75-8.
The cytologic picture in fine needle aspirates from a unique type of breast tumor, with stromal proliferation of osteoclastlike giant cells, cartilaginous metaplasia and metaplastic spindle-shaped carcinomatous cells, is described. In this case, an erroneous cytologic diagnosis of fat necrosis associated with a rich component of reactive fibroblasts was made. This false-negative report, which was mainly due to lack of an obvious carcinomatous component in the aspirated material, is discussed with emphasis placed on the need to exclude spindle cell metaplasia in a breast carcinoma whose aspirates are characterized by a rich component of spindle-shaped cells.
描述了一种独特类型乳腺肿瘤细针穿刺抽吸物的细胞学表现，其具有破骨细胞样巨细胞的间质增生、软骨化生和化生的梭形癌细胞。在该病例中，曾做出与丰富的反应性成纤维细胞成分相关的脂肪坏死的错误细胞学诊断。讨论了这一假阴性报告，主要原因是抽吸物中缺乏明显的癌成分，并强调在以丰富的梭形细胞成分为特征的乳腺癌细针穿刺抽吸物中需要排除梭形细胞化生。
